Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy

Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is a pediatric genetic disease, characterized by motor neuron (MN) death, leading to progressive muscle weakness, respiratory failure, and, in the most severe cases, to death. Abnormalities at the neuromuscular junction (NMJ) have been reported in SMA, including neurofi...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Marina Boido, Elena De Amicis, Valeria Valsecchi, Marco Trevisan, Ugo Ala, Markus A. Ruegg, Stefan Hettwer, Alessandro Vercelli
Formáid:	Alt
Teanga:	English
Foilsithe / Cruthaithe:	Frontiers Media S.A. 2018-01-01
Sraith:	Frontiers in Cellular Neuroscience
Ábhair:	motor neuron disease neuromuscular junctions muscle motor performance innervation
Rochtain ar líne:	http://journal.frontiersin.org/article/10.3389/fncel.2018.00017/full

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