2066 Functional characterization of mutant BRCA1
OBJECTIVES/SPECIFIC AIMS: The objective of this work is to determine the mechanistic consequences of BRCA1 mutants in inter-strand crosslink (ICL) repair. METHODS/STUDY POPULATION: Our lab uses Xenopus egg extracts to study ICL repair. These extracts can be depleted of endogenous BRCA1 by immunoprec...
Main Authors: | John Barrows, David Long |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2018-06-01
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Series: | Journal of Clinical and Translational Science |
Online Access: | https://www.cambridge.org/core/product/identifier/S2059866118000778/type/journal_article |
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