Encefalomielite aguda disseminada: relato de caso
To describe the case of a child diagnosed with Acute Disseminated Encephalomyelitis who presented recurrence. Child, from Belém, female, 10-years-old, started symptoms of hypoactivity and vomiting, evolving with altered level of consciousness, loss of sphincter control, decreased muscle strength, he...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Pediatria
2023-06-01
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| Series: | Residência Pediátrica |
| Subjects: | |
| Online Access: | https://residenciapediatrica.com.br/detalhes/1341/encefalomielite%20aguda%20disseminada-%20relato%20de%20caso |
| _version_ | 1797458404289019904 |
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| author | Wanessa Cardoso Praia Quezia Denise Cortez Morais Juliana Pastana Ramos de Freitas |
| author_facet | Wanessa Cardoso Praia Quezia Denise Cortez Morais Juliana Pastana Ramos de Freitas |
| author_sort | Wanessa Cardoso Praia |
| collection | DOAJ |
| description | To describe the case of a child diagnosed with Acute Disseminated Encephalomyelitis who presented recurrence. Child, from Belém, female, 10-years-old, started symptoms of hypoactivity and vomiting, evolving with altered level of consciousness, loss of sphincter control, decreased muscle strength, hemiparesis and aphasia. The cerebrospinal fluid was collected and meningitis was discarded. Was performed a computed tomography scan of the skull with a hypodense image in the deep parietal region. Corticosteroid therapy was started in low doses, showing a slight improvement. She was transferred to a referral hospital in pediatric neurology, with hypoactivity and altered neurological examination on the left. Magnetic resonance imaging of the brain and spinal cord showed images suggestive of Acute Disseminated Encephalomyelitis, and pulse therapy (methylprednisolone) was started. Afterwards, clinical progress was observed: improved speech, motor skills and sphincter control. Patient was discharged from hospital with corticosteroid maintenance and multidisciplinary rehabilitation. She remained clinically well, with good recovery. After five months, she evolved again with neurological manifestations, being considered a re-acute demyelinating condition, starting pulse therapy with methylprednisolone. She showed only partial improvement in symptoms. A new neuroimaging showing lesions still active. Chosen to perform immunoglobulin, evolving with significant clinical improvement. This disease starts with nonspecific prodromes and afterwards neurological symptoms will appears. The diagnosis is made through the neurological clinic and neuroimaging with classic alterations of the disease. Treatment is based on pulse therapy with methylprednisolone, followed by prednisolone. Intravenous human immunoglobulin is used as an option for cortic-resistant or relapsing patients. |
| first_indexed | 2024-03-09T16:36:38Z |
| format | Article |
| id | doaj.art-d274b8476ef14cebb84e08e9b9bcd297 |
| institution | Directory Open Access Journal |
| issn | 2236-6814 |
| language | English |
| last_indexed | 2024-03-09T16:36:38Z |
| publishDate | 2023-06-01 |
| publisher | Sociedade Brasileira de Pediatria |
| record_format | Article |
| series | Residência Pediátrica |
| spelling | doaj.art-d274b8476ef14cebb84e08e9b9bcd2972023-11-24T14:56:11ZengSociedade Brasileira de PediatriaResidência Pediátrica2236-68142023-06-0113210.25060/residpediatr-2023.v13n2-562Encefalomielite aguda disseminada: relato de casoWanessa Cardoso Praia0Quezia Denise Cortez Morais1Juliana Pastana Ramos de Freitas2Fundação Santa Casa de Misericórdia do Pará, Pediatria - Belém - Pará - BrasilFundação Santa Casa de Misericórdia do Pará, Pediatria - Belém - Pará - BrasilFundação Santa Casa de Misericórdia do Pará, Neurologia Pediátrica - Belém - Pará - BrasilTo describe the case of a child diagnosed with Acute Disseminated Encephalomyelitis who presented recurrence. Child, from Belém, female, 10-years-old, started symptoms of hypoactivity and vomiting, evolving with altered level of consciousness, loss of sphincter control, decreased muscle strength, hemiparesis and aphasia. The cerebrospinal fluid was collected and meningitis was discarded. Was performed a computed tomography scan of the skull with a hypodense image in the deep parietal region. Corticosteroid therapy was started in low doses, showing a slight improvement. She was transferred to a referral hospital in pediatric neurology, with hypoactivity and altered neurological examination on the left. Magnetic resonance imaging of the brain and spinal cord showed images suggestive of Acute Disseminated Encephalomyelitis, and pulse therapy (methylprednisolone) was started. Afterwards, clinical progress was observed: improved speech, motor skills and sphincter control. Patient was discharged from hospital with corticosteroid maintenance and multidisciplinary rehabilitation. She remained clinically well, with good recovery. After five months, she evolved again with neurological manifestations, being considered a re-acute demyelinating condition, starting pulse therapy with methylprednisolone. She showed only partial improvement in symptoms. A new neuroimaging showing lesions still active. Chosen to perform immunoglobulin, evolving with significant clinical improvement. This disease starts with nonspecific prodromes and afterwards neurological symptoms will appears. The diagnosis is made through the neurological clinic and neuroimaging with classic alterations of the disease. Treatment is based on pulse therapy with methylprednisolone, followed by prednisolone. Intravenous human immunoglobulin is used as an option for cortic-resistant or relapsing patients.https://residenciapediatrica.com.br/detalhes/1341/encefalomielite%20aguda%20disseminada-%20relato%20de%20casoencephalomyelitisacute disseminateddemyelinating autoimmune diseasescns |
| spellingShingle | Wanessa Cardoso Praia Quezia Denise Cortez Morais Juliana Pastana Ramos de Freitas Encefalomielite aguda disseminada: relato de caso Residência Pediátrica encephalomyelitis acute disseminated demyelinating autoimmune diseases cns |
| title | Encefalomielite aguda disseminada: relato de caso |
| title_full | Encefalomielite aguda disseminada: relato de caso |
| title_fullStr | Encefalomielite aguda disseminada: relato de caso |
| title_full_unstemmed | Encefalomielite aguda disseminada: relato de caso |
| title_short | Encefalomielite aguda disseminada: relato de caso |
| title_sort | encefalomielite aguda disseminada relato de caso |
| topic | encephalomyelitis acute disseminated demyelinating autoimmune diseases cns |
| url | https://residenciapediatrica.com.br/detalhes/1341/encefalomielite%20aguda%20disseminada-%20relato%20de%20caso |
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