Effects of Gestational and Lactational Lead Exposure and High Fat Diet Feeding on Cerebellar Development of Postnatal Rat Offspring

Effects of Gestational and Lactational Lead Exposure and High Fat Diet Feeding on Cerebellar Development of Postnatal Rat Offspring

Obesity and heavy metals, such as lead (Pb), are detrimental to the adult brain because they impair cognitive function and structural plasticity. However, the effects of co-administration of Pb and a high-fat diet (HFD) on the developing cerebellum is not clearly elucidated. We investigated the effe...

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Bibliographic Details
Main Authors: Jin Seok Seo, Shin Hyo Lee, Hyung-Sun Won, Miyoung Yang, Sang-Seop Nahm, Sung Min Nam
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Nutrients
Subjects:
lead (Pb)
high fat diet
cerebellar development
Purkinje cell
rat
Online Access:https://www.mdpi.com/2072-6643/15/20/4325

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