Role of endogenous and exogenous antioxidants in risk of six cancers: evidence from the Mendelian randomization study

Role of endogenous and exogenous antioxidants in risk of six cancers: evidence from the Mendelian randomization study

Background: Although oxidative stress is known to contribute to cancer, and endogenous and exogenous antioxidants are thought to prevent tumorigenesis by suppressing oxidative stress-induced DNA damage, antioxidants have also been reported to show negative effects on tumor formation, necessitating c...

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Bibliographic Details
Main Authors: Jiahao Zhu, Jie Lian, Xin Wang, Ren Wang, Xiangyi Pang, Benjie Xu, Xing Wang, Chenyang Li, Shengjun Ji, Haibo Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Pharmacology
Subjects:
oxidative stress
endogenous antioxidant
exogenous antioxidant
cancer prevention
Mendelian randomization study
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1185850/full

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