Multimodal imaging characteristics of hydroxychloroquine retinopathy

Hydroxychloroquine (HCQ) is known to cause retinal toxicity. Early detection of the toxicity is necessary to stop the drug in time. Multicolor imaging (MC) is a new noninvasive retinal imaging modality that simultaneously acquires three reflectance images of the retina using three individual lasers...

Full description

Bibliographic Details
Main Authors: Kumar Saurabh, Rupak Roy, Nicey Roy Thomas, Maitreyi Chowdhury
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=2;spage=324;epage=327;aulast=Saurabh
_version_ 1798044130772779008
author Kumar Saurabh
Rupak Roy
Nicey Roy Thomas
Maitreyi Chowdhury
author_facet Kumar Saurabh
Rupak Roy
Nicey Roy Thomas
Maitreyi Chowdhury
author_sort Kumar Saurabh
collection DOAJ
description Hydroxychloroquine (HCQ) is known to cause retinal toxicity. Early detection of the toxicity is necessary to stop the drug in time. Multicolor imaging (MC) is a new noninvasive retinal imaging modality that simultaneously acquires three reflectance images of the retina using three individual lasers producing a composite image, thereby allowing analysis of changes at various levels within the retina. It is a new and promising addition to the retinal imaging armory. MC characteristics of HCQ toxicity are hitherto unreported. A 61-year-old female presented with history of HCQ intake (400 mg/day) for the last 6 years. She had retinopathy in both eyes. Multicolor composite image showed circumscribed perifoveal arcuate area of darkening, and infrared reflectance showed speckled hyperreflecetance in both eyes. MC imaging shows definite changes in HCQ toxicity, and it might emerge as a possible screening tool in future.
first_indexed 2024-04-11T22:58:48Z
format Article
id doaj.art-d281c09f20c541628e021b06830c8456
institution Directory Open Access Journal
issn 0301-4738
1998-3689
language English
last_indexed 2024-04-11T22:58:48Z
publishDate 2018-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Ophthalmology
spelling doaj.art-d281c09f20c541628e021b06830c84562022-12-22T03:58:17ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892018-01-0166232432710.4103/ijo.IJO_787_17Multimodal imaging characteristics of hydroxychloroquine retinopathyKumar SaurabhRupak RoyNicey Roy ThomasMaitreyi ChowdhuryHydroxychloroquine (HCQ) is known to cause retinal toxicity. Early detection of the toxicity is necessary to stop the drug in time. Multicolor imaging (MC) is a new noninvasive retinal imaging modality that simultaneously acquires three reflectance images of the retina using three individual lasers producing a composite image, thereby allowing analysis of changes at various levels within the retina. It is a new and promising addition to the retinal imaging armory. MC characteristics of HCQ toxicity are hitherto unreported. A 61-year-old female presented with history of HCQ intake (400 mg/day) for the last 6 years. She had retinopathy in both eyes. Multicolor composite image showed circumscribed perifoveal arcuate area of darkening, and infrared reflectance showed speckled hyperreflecetance in both eyes. MC imaging shows definite changes in HCQ toxicity, and it might emerge as a possible screening tool in future.http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=2;spage=324;epage=327;aulast=SaurabhHydroxychloroquinemulticolour imagingmultimodal imagingretinal toxicity
spellingShingle Kumar Saurabh
Rupak Roy
Nicey Roy Thomas
Maitreyi Chowdhury
Multimodal imaging characteristics of hydroxychloroquine retinopathy
Indian Journal of Ophthalmology
Hydroxychloroquine
multicolour imaging
multimodal imaging
retinal toxicity
title Multimodal imaging characteristics of hydroxychloroquine retinopathy
title_full Multimodal imaging characteristics of hydroxychloroquine retinopathy
title_fullStr Multimodal imaging characteristics of hydroxychloroquine retinopathy
title_full_unstemmed Multimodal imaging characteristics of hydroxychloroquine retinopathy
title_short Multimodal imaging characteristics of hydroxychloroquine retinopathy
title_sort multimodal imaging characteristics of hydroxychloroquine retinopathy
topic Hydroxychloroquine
multicolour imaging
multimodal imaging
retinal toxicity
url http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=2;spage=324;epage=327;aulast=Saurabh
work_keys_str_mv AT kumarsaurabh multimodalimagingcharacteristicsofhydroxychloroquineretinopathy
AT rupakroy multimodalimagingcharacteristicsofhydroxychloroquineretinopathy
AT niceyroythomas multimodalimagingcharacteristicsofhydroxychloroquineretinopathy
AT maitreyichowdhury multimodalimagingcharacteristicsofhydroxychloroquineretinopathy