Mutational landscape and clinical outcome of pediatric acute myeloid leukemia with 11q23/KMT2A rearrangements

Mutational landscape and clinical outcome of pediatric acute myeloid leukemia with 11q23/KMT2A rearrangements

Abstract Background Alterations of 11q23/KMT2A are the most prevalent cytogenetic abnormalities in acute myeloid leukemia (AML) and the prognostic significance of 11q23/KMT2A‐rearranged AML based on various translocation partners varies among different studies. However, few studies evaluated the mol...

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Bibliographic Details
Main Authors: Ka‐Yuk Yuen, Yong Liu, Yong‐Zhuo Zhou, Yin Wang, Dun‐Hua Zhou, Jian‐Pei Fang, Lu‐Hong Xu
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Cancer Medicine
Subjects:
11q23/KMT2A
clinical outcome
gene mutations
pediatric acute myeloid leukemia
sequencing
Online Access:https://doi.org/10.1002/cam4.5026

Internet

https://doi.org/10.1002/cam4.5026

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