Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors

Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors

Affymetrix microarray data and Northern blot assays demonstrated that phospholipid transfer protein (PL222222222216) was induced 6-fold when either murine or human macrophages were incubated in the presence of ligands for the liver X receptor (LXR) and the retinoid X receptor. Two functional LXR res...

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Bibliographic Details
Main Authors: Puiying A. Mak, Heidi R. Kast-Woelbern, Andrew M. Anisfeld, Peter A. Edwards
Format: Article
Language:English
Published: Elsevier 2002-12-01
Series:Journal of Lipid Research
Subjects:
macrophages
foam cells
hepatocytes
phospholipid transfer protein
liver X receptor
retinoid X receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520327292

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