Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children
The role and frequency of human herpesviruses (HHV)-6 and -7 in central nervous system (CNS) diseases of children are unclear. Cerebrospinal fluid samples from 245 pediatric patients (median age 43 days), submitted for evaluations of possible sepsis or of neurologic symptoms, were tested for HHV-6 a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2004-08-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/10/8/03-0788_article |
| _version_ | 1818034063742599168 |
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| author | Asad Ansari Shaobing Li Mark J. Abzug Adriana Weinberg |
| author_facet | Asad Ansari Shaobing Li Mark J. Abzug Adriana Weinberg |
| author_sort | Asad Ansari |
| collection | DOAJ |
| description | The role and frequency of human herpesviruses (HHV)-6 and -7 in central nervous system (CNS) diseases of children are unclear. Cerebrospinal fluid samples from 245 pediatric patients (median age 43 days), submitted for evaluations of possible sepsis or of neurologic symptoms, were tested for HHV-6 and HHV-7 DNA by polymerase chain reaction. HHV-6 DNA was found in 3 of 245 samples, and HHV-7 was found in 0 of 245 samples. The three patients with HHV-6 DNA were <2 months of age. HHV-6 was likely pathogenic in two patients in whom meningitis was diagnosed who lacked evidence of another microbiologic cause. HHV-6 and HHV-7 are uncommon causes of CNS infection in children. HHV-6 may occasionally cause meningitis in young infants. |
| first_indexed | 2024-12-10T06:33:12Z |
| format | Article |
| id | doaj.art-d287793c581040a2ad07e7bc901375f9 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-10T06:33:12Z |
| publishDate | 2004-08-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-d287793c581040a2ad07e7bc901375f92022-12-22T01:59:01ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592004-08-011081450145410.3201/eid1008.030788Human Herpesviruses 6 and 7 and Central Nervous System Infection in ChildrenAsad AnsariShaobing LiMark J. AbzugAdriana WeinbergThe role and frequency of human herpesviruses (HHV)-6 and -7 in central nervous system (CNS) diseases of children are unclear. Cerebrospinal fluid samples from 245 pediatric patients (median age 43 days), submitted for evaluations of possible sepsis or of neurologic symptoms, were tested for HHV-6 and HHV-7 DNA by polymerase chain reaction. HHV-6 DNA was found in 3 of 245 samples, and HHV-7 was found in 0 of 245 samples. The three patients with HHV-6 DNA were <2 months of age. HHV-6 was likely pathogenic in two patients in whom meningitis was diagnosed who lacked evidence of another microbiologic cause. HHV-6 and HHV-7 are uncommon causes of CNS infection in children. HHV-6 may occasionally cause meningitis in young infants.https://wwwnc.cdc.gov/eid/article/10/8/03-0788_articlehuman herpesvirus 6human herpesvirus 7childhood meningitischildhood encephalitischildhood CNS disordersresearch |
| spellingShingle | Asad Ansari Shaobing Li Mark J. Abzug Adriana Weinberg Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children Emerging Infectious Diseases human herpesvirus 6 human herpesvirus 7 childhood meningitis childhood encephalitis childhood CNS disorders research |
| title | Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children |
| title_full | Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children |
| title_fullStr | Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children |
| title_full_unstemmed | Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children |
| title_short | Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children |
| title_sort | human herpesviruses 6 and 7 and central nervous system infection in children |
| topic | human herpesvirus 6 human herpesvirus 7 childhood meningitis childhood encephalitis childhood CNS disorders research |
| url | https://wwwnc.cdc.gov/eid/article/10/8/03-0788_article |
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