Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil
This report describes the epidemiological and clinical-evolutive characteristics of eight patients with hantavirus pulmonary syndrome (HPS) in Uberaba, Minas Gerais, Brazil. A positive history of contact with rodents was present in 100% of the cases. The time between the onset of symptoms and hospit...
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Format: | Article |
Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2002-09-01
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Series: | Memorias do Instituto Oswaldo Cruz |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600005 |
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author | Mario León Silva-Vergara José Carlos Costa Júnior Cristina Hueb Barata Vítor Guilherme Maluf Curi Carlos Giovanni Tiveron Júnior Alan César Teixeira |
author_facet | Mario León Silva-Vergara José Carlos Costa Júnior Cristina Hueb Barata Vítor Guilherme Maluf Curi Carlos Giovanni Tiveron Júnior Alan César Teixeira |
author_sort | Mario León Silva-Vergara |
collection | DOAJ |
description | This report describes the epidemiological and clinical-evolutive characteristics of eight patients with hantavirus pulmonary syndrome (HPS) in Uberaba, Minas Gerais, Brazil. A positive history of contact with rodents was present in 100% of the cases. The time between the onset of symptoms and hospital care was, on average, 3.6 days. All patients showed clinical and laboratory findings suggestive of HPS. Elevated urea and creatinine levels were observed in 6 (75%) cases, PO2 was < 60 mmHg in 100% of the cases, and a chest X-ray demonstrated a bilateral interstitial-alveolar infiltrate. The diagnosis was confirmed by the detection of IgM antibodies against Sin Nombre virus by ELISA. Three patients died as a direct consequence of HPS. |
first_indexed | 2024-03-12T18:05:48Z |
format | Article |
id | doaj.art-d288f87d8d8f4bef828baa802edad5b2 |
institution | Directory Open Access Journal |
issn | 0074-0276 1678-8060 |
language | English |
last_indexed | 2024-03-12T18:05:48Z |
publishDate | 2002-09-01 |
publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
record_format | Article |
series | Memorias do Instituto Oswaldo Cruz |
spelling | doaj.art-d288f87d8d8f4bef828baa802edad5b22023-08-02T09:28:32ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602002-09-0197678378710.1590/S0074-02762002000600005Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, BrazilMario León Silva-VergaraJosé Carlos Costa JúniorCristina Hueb BarataVítor Guilherme Maluf CuriCarlos Giovanni Tiveron JúniorAlan César TeixeiraThis report describes the epidemiological and clinical-evolutive characteristics of eight patients with hantavirus pulmonary syndrome (HPS) in Uberaba, Minas Gerais, Brazil. A positive history of contact with rodents was present in 100% of the cases. The time between the onset of symptoms and hospital care was, on average, 3.6 days. All patients showed clinical and laboratory findings suggestive of HPS. Elevated urea and creatinine levels were observed in 6 (75%) cases, PO2 was < 60 mmHg in 100% of the cases, and a chest X-ray demonstrated a bilateral interstitial-alveolar infiltrate. The diagnosis was confirmed by the detection of IgM antibodies against Sin Nombre virus by ELISA. Three patients died as a direct consequence of HPS.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600005hantavirushantavirus pulmonary syndrome/HPSSin Nombre virusMinas GeraisBrazil |
spellingShingle | Mario León Silva-Vergara José Carlos Costa Júnior Cristina Hueb Barata Vítor Guilherme Maluf Curi Carlos Giovanni Tiveron Júnior Alan César Teixeira Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil Memorias do Instituto Oswaldo Cruz hantavirus hantavirus pulmonary syndrome/HPS Sin Nombre virus Minas Gerais Brazil |
title | Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil |
title_full | Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil |
title_fullStr | Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil |
title_full_unstemmed | Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil |
title_short | Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil |
title_sort | hantavirus pulmonary syndrome in uberaba minas gerais brazil |
topic | hantavirus hantavirus pulmonary syndrome/HPS Sin Nombre virus Minas Gerais Brazil |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600005 |
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