Wild-Type MIC Distribution for Re-evaluating the Critical Concentration of Anti-TB Drugs and Pharmacodynamics Among Tuberculosis Patients From South India

Wild-Type MIC Distribution for Re-evaluating the Critical Concentration of Anti-TB Drugs and Pharmacodynamics Among Tuberculosis Patients From South India

The World Health Organization (WHO) has developed specific guidelines for critical concentrations (CCs) of antibiotics used for tuberculosis (TB) treatment, which is universally followed for drug susceptibility testing (DST) of clinical specimens. However, the CC of drugs can differ significantly am...

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Bibliographic Details
Main Authors: Azger Dusthackeer, Shainaba A. Saadhali, Manonanthini Thangam, Sameer Hassan, Mahizhaveni Balasubramanian, Angayarkani Balasubramanian, Geetha Ramachandran, A. K. Hemanth Kumar, Kannan Thiruvenkadam, Govindarajan Shanmugam, Christy Rosaline Nirmal, Sam Ebenezer Rajadas, Sucharitha Kannappan Mohanvel, Rajesh Mondal
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Microbiology
Subjects:
tuberculosis
minimum inhibitory concentration (MIC)
critical concentration
drug resistance
pharmacodynamics (PD)
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01182/full

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