Cross-species comparisons reveal resistance of human skeletal stem cells to inhibition by non-steroidal anti-inflammatory drugs
Fracture healing is highly dependent on an early inflammatory response in which prostaglandin production by cyclo-oxygenases (COX) plays a crucial role. Current patient analgesia regimens favor opioids over Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) since the latter have been implicated in delay...
Main Authors: | L. Henry Goodnough, Thomas H. Ambrosi, Holly M. Steininger, M. Gohazrua K. Butler, Malachia Y. Hoover, HyeRan Choo, Noelle L. Van Rysselberghe, Michael J. Bellino, Julius A. Bishop, Michael J. Gardner, Charles K. F. Chan |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-08-01
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Series: | Frontiers in Endocrinology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.924927/full |
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