| Summary: | Jingyong Xu,1 Yanbin Wang,2 Hongyuan Cui,1 Jian Chen1 1Department of General Surgery, Beijing Hospital, National Centre of Gerontology, Beijing 100730, People’s Republic of China; 2Department of General Surgery, Beijing Aero Space General Hospital, Beijing 100076, People’s Republic of ChinaCorrespondence: Jian ChenDepartment of General Surgery, Beijing Hospital, Beijing 100730, People’s Republic of ChinaEmail chenjian0265@bjhmoh.cnBackground: Intra-abdominal Clostridium perfringens, especially liver infection, is rare and fatal. It often occurs in patients with immunodeficiency due to various factors, such as cancer, diabetes mellitus, and organ transplantation. The identification of gram-positive bacilli in septicemia, the presence of gas-forming liver damage and intravascular hemolysis are manifestations of Clostridium perfringens infection. The episode deteriorates rapidly and has a high mortality rate.Case presentation: This case involved a 60-year-old man with infection onset 2 weeks after common bile duct stenting for obstructive jaundice caused by unresectable pancreatic cancer. Abdominal computed tomography (CT) revealed gas-containing lesions in the liver. Blood culture showed Clostridium perfringens. Though aggressively rescued, he died within 24 hrs after admission.Conclusion: Clostridium perfringens liver infection is rare but leads to a severe prognosis rapidly. High awareness of this condition is key for early diagnosis and effective treatment.Keywords: liver infection, Clostridium perfringens, stenting, pancreatic cancer
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