Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study
Abstract Background Previous studies have shown that marital status was associated with stages and survival in patients with melanoma or Merkel cell carcinoma. To date, the impacts of marital status on stage and survival in patients with mycosis fungoides (MF) have not been determined yet. Methods A...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-10-01
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| Series: | Cancer Medicine |
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| Online Access: | https://doi.org/10.1002/cam4.4232 |
| _version_ | 1819152348487876608 |
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| author | Ling‐Xiao Xing Jing Zhang Hui Shen Xiao‐Lu Tang Lu He Jia‐Zhu Wu Jian‐Yong Li Yi Miao |
| author_facet | Ling‐Xiao Xing Jing Zhang Hui Shen Xiao‐Lu Tang Lu He Jia‐Zhu Wu Jian‐Yong Li Yi Miao |
| author_sort | Ling‐Xiao Xing |
| collection | DOAJ |
| description | Abstract Background Previous studies have shown that marital status was associated with stages and survival in patients with melanoma or Merkel cell carcinoma. To date, the impacts of marital status on stage and survival in patients with mycosis fungoides (MF) have not been determined yet. Methods A total of 3375 eligible cases diagnosed from 2004 to 2015 were included from the Surveillance, Epidemiology, and End Results (SEER) database. Association of marital status with stage and survival in patients with MF was analyzed. Results Married patients were more likely to be diagnosed at T1 stage (p = 0.041). And married patients were less likely to present with lymph node involvement (p = 0.007). More favorable overall survival (p < 0.001) and cancer‐specific survival (p < 0.001) were demonstrated in married patients as compared with divorced patients or widowed patients. A clinically feasible prognostic model including marital status, age, sex, race, and stage at presentation was constructed. Conclusion Married marital status was associated with earlier stage at diagnosis and longer survival compared with divorced or widowed marital status in patients with MF. |
| first_indexed | 2024-12-22T14:47:52Z |
| format | Article |
| id | doaj.art-d2930eb501ff4bae8f61a337820eba9b |
| institution | Directory Open Access Journal |
| issn | 2045-7634 |
| language | English |
| last_indexed | 2024-12-22T14:47:52Z |
| publishDate | 2021-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj.art-d2930eb501ff4bae8f61a337820eba9b2022-12-21T18:22:23ZengWileyCancer Medicine2045-76342021-10-0110207320732910.1002/cam4.4232Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based studyLing‐Xiao Xing0Jing Zhang1Hui Shen2Xiao‐Lu Tang3Lu He4Jia‐Zhu Wu5Jian‐Yong Li6Yi Miao7Department of Hematology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province Hospital Nanjing ChinaDepartment of Hematology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province Hospital Nanjing ChinaDepartment of Hematology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province Hospital Nanjing ChinaDepartment of Hematology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province Hospital Nanjing ChinaDepartment of Hematology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province Hospital Nanjing ChinaDepartment of Hematology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province Hospital Nanjing ChinaDepartment of Hematology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province Hospital Nanjing ChinaDepartment of Hematology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province Hospital Nanjing ChinaAbstract Background Previous studies have shown that marital status was associated with stages and survival in patients with melanoma or Merkel cell carcinoma. To date, the impacts of marital status on stage and survival in patients with mycosis fungoides (MF) have not been determined yet. Methods A total of 3375 eligible cases diagnosed from 2004 to 2015 were included from the Surveillance, Epidemiology, and End Results (SEER) database. Association of marital status with stage and survival in patients with MF was analyzed. Results Married patients were more likely to be diagnosed at T1 stage (p = 0.041). And married patients were less likely to present with lymph node involvement (p = 0.007). More favorable overall survival (p < 0.001) and cancer‐specific survival (p < 0.001) were demonstrated in married patients as compared with divorced patients or widowed patients. A clinically feasible prognostic model including marital status, age, sex, race, and stage at presentation was constructed. Conclusion Married marital status was associated with earlier stage at diagnosis and longer survival compared with divorced or widowed marital status in patients with MF.https://doi.org/10.1002/cam4.4232marital statusmycosis fungoidesprognosisSEER |
| spellingShingle | Ling‐Xiao Xing Jing Zhang Hui Shen Xiao‐Lu Tang Lu He Jia‐Zhu Wu Jian‐Yong Li Yi Miao Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study Cancer Medicine marital status mycosis fungoides prognosis SEER |
| title | Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study |
| title_full | Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study |
| title_fullStr | Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study |
| title_full_unstemmed | Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study |
| title_short | Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study |
| title_sort | association of marital status with stage and survival in patients with mycosis fungoides a population based study |
| topic | marital status mycosis fungoides prognosis SEER |
| url | https://doi.org/10.1002/cam4.4232 |
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