The components data of fuzheng huayu extracts, cordyceps sinensis mycelia polysaccharide, gypenosides and amygdalin

Fuzheng Huayu (FZHY) capsule is a traditional Chinese medicine composed of six Chinese medicinal herbs Tian et al. [1] and approved by China food and drug administration for liver fibrosis treatment [2,3] Liu et al., 2009 and Liu et al., 2005. CGA formula consisting of Cordyeps sinensis polysacchari...

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Main Authors: Wei Liu, Zhixiong Li, Zhaolin Sun, Yongbin Xu, Shunchun Wang, Yiyang Hu, Jinghua Peng
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S235234091930441X
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author Wei Liu
Zhixiong Li
Zhaolin Sun
Yongbin Xu
Shunchun Wang
Yiyang Hu
Jinghua Peng
author_facet Wei Liu
Zhixiong Li
Zhaolin Sun
Yongbin Xu
Shunchun Wang
Yiyang Hu
Jinghua Peng
author_sort Wei Liu
collection DOAJ
description Fuzheng Huayu (FZHY) capsule is a traditional Chinese medicine composed of six Chinese medicinal herbs Tian et al. [1] and approved by China food and drug administration for liver fibrosis treatment [2,3] Liu et al., 2009 and Liu et al., 2005. CGA formula consisting of Cordyeps sinensis polysaccharide (CS-PS), gypenosides (G), and amygdalin (A), are derived from FZHY formula. It is necessary to identify the chemical profile of FZHY and CGA formula to describe the mechanisms and the corresponding components of anti-fibrosis. It is showed that FZHY contains adenosine (5.21 mg/g), amygdalin (5.31 mg/g), salvianolic acid b (18.22 mg/g) and deoxyschizandrin (2.62 mg/g), respectively. CS-PS contained 60.5 ± 2.2% total carbohydrate, including 14.17% arabinose, 25.35% glucose and 60.48% galactose. Gypenosides contain 10.34% gypenosides XLIX and 16.58% gypenosides A. These data provide the primary chemical profile of FZHY and CGA formula and an example for components analysis of traditional Chinese medicine. Keywords: High-performance liquid chromatography, Traditional Chinese medicine, Fuzheng huayu capsule, Cordyeps sinensis polysaccharide, Gypenosides
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spelling doaj.art-d2966dbbe7a542c9b80cef8c4c34d6fd2022-12-21T22:32:18ZengElsevierData in Brief2352-34092019-08-0125The components data of fuzheng huayu extracts, cordyceps sinensis mycelia polysaccharide, gypenosides and amygdalinWei Liu0Zhixiong Li1Zhaolin Sun2Yongbin Xu3Shunchun Wang4Yiyang Hu5Jinghua Peng6Institute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, ChinaShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, ChinaShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, ChinaInstitute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, ChinaInstitute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, ChinaInstitute of Clinical Pharmacology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Key Laboratory of Liver and Kidney Diseases (Shanghai University of Traditional Chinese Medicine), Ministry of Education, Shanghai, 201203, China; Shanghai Key Laboratory of Traditional Chinese Clinical Medicine, Shanghai, 201203, ChinaInstitute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Key Laboratory of Liver and Kidney Diseases (Shanghai University of Traditional Chinese Medicine), Ministry of Education, Shanghai, 201203, China; Shanghai Key Laboratory of Traditional Chinese Clinical Medicine, Shanghai, 201203, China; Corresponding author. Institute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.Fuzheng Huayu (FZHY) capsule is a traditional Chinese medicine composed of six Chinese medicinal herbs Tian et al. [1] and approved by China food and drug administration for liver fibrosis treatment [2,3] Liu et al., 2009 and Liu et al., 2005. CGA formula consisting of Cordyeps sinensis polysaccharide (CS-PS), gypenosides (G), and amygdalin (A), are derived from FZHY formula. It is necessary to identify the chemical profile of FZHY and CGA formula to describe the mechanisms and the corresponding components of anti-fibrosis. It is showed that FZHY contains adenosine (5.21 mg/g), amygdalin (5.31 mg/g), salvianolic acid b (18.22 mg/g) and deoxyschizandrin (2.62 mg/g), respectively. CS-PS contained 60.5 ± 2.2% total carbohydrate, including 14.17% arabinose, 25.35% glucose and 60.48% galactose. Gypenosides contain 10.34% gypenosides XLIX and 16.58% gypenosides A. These data provide the primary chemical profile of FZHY and CGA formula and an example for components analysis of traditional Chinese medicine. Keywords: High-performance liquid chromatography, Traditional Chinese medicine, Fuzheng huayu capsule, Cordyeps sinensis polysaccharide, Gypenosideshttp://www.sciencedirect.com/science/article/pii/S235234091930441X
spellingShingle Wei Liu
Zhixiong Li
Zhaolin Sun
Yongbin Xu
Shunchun Wang
Yiyang Hu
Jinghua Peng
The components data of fuzheng huayu extracts, cordyceps sinensis mycelia polysaccharide, gypenosides and amygdalin
Data in Brief
title The components data of fuzheng huayu extracts, cordyceps sinensis mycelia polysaccharide, gypenosides and amygdalin
title_full The components data of fuzheng huayu extracts, cordyceps sinensis mycelia polysaccharide, gypenosides and amygdalin
title_fullStr The components data of fuzheng huayu extracts, cordyceps sinensis mycelia polysaccharide, gypenosides and amygdalin
title_full_unstemmed The components data of fuzheng huayu extracts, cordyceps sinensis mycelia polysaccharide, gypenosides and amygdalin
title_short The components data of fuzheng huayu extracts, cordyceps sinensis mycelia polysaccharide, gypenosides and amygdalin
title_sort components data of fuzheng huayu extracts cordyceps sinensis mycelia polysaccharide gypenosides and amygdalin
url http://www.sciencedirect.com/science/article/pii/S235234091930441X
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