Prospective study of atopic status in infants of the cohort in Tokyo, Japan
Several risk factors for the development of allergic diseases are considered including, for example, the level of IgE in cord blood or in the peripheral blood of neonates and the antigenic effect of some foods that are ingested by both babies and mothers during pregnancy and during the lactation per...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
1997-01-01
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| Series: | Allergology International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893015316038 |
| _version_ | 1811233901962592256 |
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| author | Tsutomu Iwata Hiroshi Hayakawa Fusako Komoda Masae Koseki Tatsuko Miyakawa Toyoo Sakurayama Kaeko Yamasaki Michie Honjou Noriko Hirakawa Kazuko Inoue Naohiro Hohashi Chieko Sugishita |
| author_facet | Tsutomu Iwata Hiroshi Hayakawa Fusako Komoda Masae Koseki Tatsuko Miyakawa Toyoo Sakurayama Kaeko Yamasaki Michie Honjou Noriko Hirakawa Kazuko Inoue Naohiro Hohashi Chieko Sugishita |
| author_sort | Tsutomu Iwata |
| collection | DOAJ |
| description | Several risk factors for the development of allergic diseases are considered including, for example, the level of IgE in cord blood or in the peripheral blood of neonates and the antigenic effect of some foods that are ingested by both babies and mothers during pregnancy and during the lactation period. However, not all infants with atopic diathesis develop allergic diseases. To clarify the risk factors and the mechanism for developing allergic diseases, particularly bronchial asthma (BA), we prospectively investigated atopic diatheses and symptoms in children in a cohort using a questionnaire method. The factors correlated to development of allergic diseases, as a whole, at the age of 5–6 years were atopic family history and any allergic symptom at 4 months of age. However, not all subjects with atopic dermatitis developed BA later on. High levels of total IgE and positive IgE antibody against egg white were not risk factors for developing BA at the age of 5–6 years. |
| first_indexed | 2024-04-12T11:27:00Z |
| format | Article |
| id | doaj.art-d296ab713b8e4e2a91fdc74eba0c35aa |
| institution | Directory Open Access Journal |
| issn | 1323-8930 |
| language | English |
| last_indexed | 2024-04-12T11:27:00Z |
| publishDate | 1997-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Allergology International |
| spelling | doaj.art-d296ab713b8e4e2a91fdc74eba0c35aa2022-12-22T03:35:12ZengElsevierAllergology International1323-89301997-01-0146422122510.2332/allergolint.46.221Prospective study of atopic status in infants of the cohort in Tokyo, JapanTsutomu Iwata0Hiroshi Hayakawa1Fusako Komoda2Masae Koseki3Tatsuko Miyakawa4Toyoo Sakurayama5Kaeko Yamasaki6Michie Honjou7Noriko Hirakawa8Kazuko Inoue9Naohiro Hohashi10Chieko Sugishita11Department of Pediatrics, Mejirodai Campus, JapanDepartment of Pediatrics, Mejirodai Campus, JapanDepartment of Pediatrics, Mejirodai Campus, JapanDepartment of Public Health and Health Centre, Office of Bunkyo-District, JapanDepartment of Public Health and Health Centre, Office of Bunkyo-District, JapanDepartment of Public Health and Health Centre, Office of Bunkyo-District, JapanDepartment of Public Health and Health Centre, Office of Bunkyo-District, JapanDepartment of Pediatrics, Second Hospital of Tokyo Women's Medical College, JapanDepartment of Pediatrics, Second Hospital of Tokyo Women's Medical College, JapanDepartment of Pediatrics, Tokyo Metropolitan Hiroo Hospital, Tokyo, JapanDepartment of Family Nursing, Faculty of Medicine, University of Tokyo, JapanDepartment of Family Nursing, Faculty of Medicine, University of Tokyo, JapanSeveral risk factors for the development of allergic diseases are considered including, for example, the level of IgE in cord blood or in the peripheral blood of neonates and the antigenic effect of some foods that are ingested by both babies and mothers during pregnancy and during the lactation period. However, not all infants with atopic diathesis develop allergic diseases. To clarify the risk factors and the mechanism for developing allergic diseases, particularly bronchial asthma (BA), we prospectively investigated atopic diatheses and symptoms in children in a cohort using a questionnaire method. The factors correlated to development of allergic diseases, as a whole, at the age of 5–6 years were atopic family history and any allergic symptom at 4 months of age. However, not all subjects with atopic dermatitis developed BA later on. High levels of total IgE and positive IgE antibody against egg white were not risk factors for developing BA at the age of 5–6 years.http://www.sciencedirect.com/science/article/pii/S1323893015316038atopic dermatitisatopybronchial asthmacohort studyinfantsrisk factorSeveral risk factors for the development |
| spellingShingle | Tsutomu Iwata Hiroshi Hayakawa Fusako Komoda Masae Koseki Tatsuko Miyakawa Toyoo Sakurayama Kaeko Yamasaki Michie Honjou Noriko Hirakawa Kazuko Inoue Naohiro Hohashi Chieko Sugishita Prospective study of atopic status in infants of the cohort in Tokyo, Japan Allergology International atopic dermatitis atopy bronchial asthma cohort study infants risk factor Several risk factors for the development |
| title | Prospective study of atopic status in infants of the cohort in Tokyo, Japan |
| title_full | Prospective study of atopic status in infants of the cohort in Tokyo, Japan |
| title_fullStr | Prospective study of atopic status in infants of the cohort in Tokyo, Japan |
| title_full_unstemmed | Prospective study of atopic status in infants of the cohort in Tokyo, Japan |
| title_short | Prospective study of atopic status in infants of the cohort in Tokyo, Japan |
| title_sort | prospective study of atopic status in infants of the cohort in tokyo japan |
| topic | atopic dermatitis atopy bronchial asthma cohort study infants risk factor Several risk factors for the development |
| url | http://www.sciencedirect.com/science/article/pii/S1323893015316038 |
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