Treatment of Morgellons disease with doxycycline

Abstract Morgellons disease (MD) is a rare dermatopathy characterized by nonspecific symptoms and the production of multicolored fibers and granular tissue from diffuse skin ulcerations which are described as being either pruritic or painful. The etiology of MD is currently unknown; previous studies...

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Main Authors: Jeff F. Zhang, Keerthy Gopalakrishnan, Daniel J. Molloy
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.5148
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author Jeff F. Zhang
Keerthy Gopalakrishnan
Daniel J. Molloy
author_facet Jeff F. Zhang
Keerthy Gopalakrishnan
Daniel J. Molloy
author_sort Jeff F. Zhang
collection DOAJ
description Abstract Morgellons disease (MD) is a rare dermatopathy characterized by nonspecific symptoms and the production of multicolored fibers and granular tissue from diffuse skin ulcerations which are described as being either pruritic or painful. The etiology of MD is currently unknown; previous studies have suggested both psychiatric and infectious causes, with increasing interest over the previous decade in elaborating a possible pathogenesis for the disease secondary to infection by Borrelia species. We report a middle‐aged Caucasian female who developed symptoms of MD in the days following exposure to a tick bite after spending an afternoon hiking through a wooded area. She was subsequently treated with a course of Doxycycline and found on two‐week follow‐up to have complete remission of her symptoms. This case report further supports the theory for an infectious etiology of MD and encourages future studies into its pathophysiology.
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spelling doaj.art-d29848feaded42f3bc5a719384c81bb22022-12-22T04:16:19ZengWileyClinical Case Reports2050-09042021-12-01912n/an/a10.1002/ccr3.5148Treatment of Morgellons disease with doxycyclineJeff F. Zhang0Keerthy Gopalakrishnan1Daniel J. Molloy2Jacobs School of Medicine and Biomedical Sciences University at Buffalo Buffalo New York USASRM Medical College Hospital and Research Centre Kattankulathur Kanchipuram IndiaSt. Vincent Health Center, Sisters of Charity Hospital Buffalo New York USAAbstract Morgellons disease (MD) is a rare dermatopathy characterized by nonspecific symptoms and the production of multicolored fibers and granular tissue from diffuse skin ulcerations which are described as being either pruritic or painful. The etiology of MD is currently unknown; previous studies have suggested both psychiatric and infectious causes, with increasing interest over the previous decade in elaborating a possible pathogenesis for the disease secondary to infection by Borrelia species. We report a middle‐aged Caucasian female who developed symptoms of MD in the days following exposure to a tick bite after spending an afternoon hiking through a wooded area. She was subsequently treated with a course of Doxycycline and found on two‐week follow‐up to have complete remission of her symptoms. This case report further supports the theory for an infectious etiology of MD and encourages future studies into its pathophysiology.https://doi.org/10.1002/ccr3.5148Borrelia burgdorferidermatopathologyDoxycyclineLyme diseaseMorgellons diseasespirochetes
spellingShingle Jeff F. Zhang
Keerthy Gopalakrishnan
Daniel J. Molloy
Treatment of Morgellons disease with doxycycline
Clinical Case Reports
Borrelia burgdorferi
dermatopathology
Doxycycline
Lyme disease
Morgellons disease
spirochetes
title Treatment of Morgellons disease with doxycycline
title_full Treatment of Morgellons disease with doxycycline
title_fullStr Treatment of Morgellons disease with doxycycline
title_full_unstemmed Treatment of Morgellons disease with doxycycline
title_short Treatment of Morgellons disease with doxycycline
title_sort treatment of morgellons disease with doxycycline
topic Borrelia burgdorferi
dermatopathology
Doxycycline
Lyme disease
Morgellons disease
spirochetes
url https://doi.org/10.1002/ccr3.5148
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