Live cell imaging of single genomic loci with quantum dot-labeled TALEs
Visualizing single genomic loci in living cells remains technically challenging. Here the authors adopt a strategy of labelling a pair of transcription activator-like effectors (TALEs) with differently coloured quantum dots and use them to identify integrated HIV-1 proviral DNA sequences in living c...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms15318 |
| _version_ | 1830144510042046464 |
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| author | Yingxin Ma Mingxiu Wang Wei Li Zhiping Zhang Xiaowei Zhang Tianwei Tan Xian-En Zhang Zongqiang Cui |
| author_facet | Yingxin Ma Mingxiu Wang Wei Li Zhiping Zhang Xiaowei Zhang Tianwei Tan Xian-En Zhang Zongqiang Cui |
| author_sort | Yingxin Ma |
| collection | DOAJ |
| description | Visualizing single genomic loci in living cells remains technically challenging. Here the authors adopt a strategy of labelling a pair of transcription activator-like effectors (TALEs) with differently coloured quantum dots and use them to identify integrated HIV-1 proviral DNA sequences in living cells. |
| first_indexed | 2024-12-17T10:08:36Z |
| format | Article |
| id | doaj.art-d299f1264a2a475692ab68c7f85c2847 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T10:08:36Z |
| publishDate | 2017-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-d299f1264a2a475692ab68c7f85c28472022-12-21T21:53:07ZengNature PortfolioNature Communications2041-17232017-05-01811810.1038/ncomms15318Live cell imaging of single genomic loci with quantum dot-labeled TALEsYingxin Ma0Mingxiu Wang1Wei Li2Zhiping Zhang3Xiaowei Zhang4Tianwei Tan5Xian-En Zhang6Zongqiang Cui7State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of SciencesState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of SciencesState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of SciencesState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of SciencesState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of SciencesBeijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical TechnologyCAS Center for Biological Macromolecules, National Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of SciencesState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of SciencesVisualizing single genomic loci in living cells remains technically challenging. Here the authors adopt a strategy of labelling a pair of transcription activator-like effectors (TALEs) with differently coloured quantum dots and use them to identify integrated HIV-1 proviral DNA sequences in living cells.https://doi.org/10.1038/ncomms15318 |
| spellingShingle | Yingxin Ma Mingxiu Wang Wei Li Zhiping Zhang Xiaowei Zhang Tianwei Tan Xian-En Zhang Zongqiang Cui Live cell imaging of single genomic loci with quantum dot-labeled TALEs Nature Communications |
| title | Live cell imaging of single genomic loci with quantum dot-labeled TALEs |
| title_full | Live cell imaging of single genomic loci with quantum dot-labeled TALEs |
| title_fullStr | Live cell imaging of single genomic loci with quantum dot-labeled TALEs |
| title_full_unstemmed | Live cell imaging of single genomic loci with quantum dot-labeled TALEs |
| title_short | Live cell imaging of single genomic loci with quantum dot-labeled TALEs |
| title_sort | live cell imaging of single genomic loci with quantum dot labeled tales |
| url | https://doi.org/10.1038/ncomms15318 |
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