Can NLR be Used in Discriminating Simple and Severe Cholecystitis in Emergency Department Admission?
INTRODUCTION: Aim: Cholecystitis is a common surgical emergency case, and the progress of simple cholecystitis to severe cholecystitis results in preoperative inflammatory and metabolic complications and a longer hospital stay. We aimed to determine whether the neutrophil-lymphocyte ratio (NLR) coul...
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| Format: | Article |
| Language: | English |
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Van Yuzuncu Yil University, School of Medicine
2021-10-01
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| Series: | Van Tıp Dergisi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-45336 |
| _version_ | 1797421286102663168 |
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| author | Hasan Basri Çetinkaya Ferhat Çay |
| author_facet | Hasan Basri Çetinkaya Ferhat Çay |
| author_sort | Hasan Basri Çetinkaya |
| collection | DOAJ |
| description | INTRODUCTION: Aim: Cholecystitis is a common surgical emergency case, and the progress of simple cholecystitis to severe cholecystitis results in preoperative inflammatory and metabolic complications and a longer hospital stay. We aimed to determine whether the neutrophil-lymphocyte ratio (NLR) could help discriminate between simple and severe cholecystitis in emergency department (ED) admissions. METHODS: Materials and Methods: All patients who were aged 18 or older, were diagnosed with cholecystitis, and presented to ED were included in our retrospective study. Blood laboratory values of patients who were diagnosed with cholecystitis in ED and whose preoperative diagnosis was confirmed were taken. Patients with secondary changes associated with cholecystitis, such as gangrenous cholecystitis and gallbladder perforation, were included in the severe cholecystitis group. RESULTS: Results: The study consisted of 54 patients, including 45 (83.33%) with simple cholecystitis and 9 (16.67%) with severe cholecystitis. Of the 54 patients, 28 (51.85%) were male, 26 (48.15%) were female, and the median age was 71 years (minimum-maximum: 27-94). NLR was found significantly higher in the severe cholecystitis group compared to the simple cholecystitis group (p <0.001). Besides, there was a significant difference between the two groups in terms of CRP, WBC, neutrophil, and lymphocyte values. DISCUSSION AND CONCLUSION: Conclusion: Early discrimination of simple and severe cholecystitis in patients presenting to the emergency department with right upper quadrant pain is important in terms of patient management. We think it may be useful to utilize the NLR ratio to discriminate between simple and severe cholecystitis. |
| first_indexed | 2024-03-09T07:13:43Z |
| format | Article |
| id | doaj.art-d29a011a76d44b109a3c99c8ac4ceb54 |
| institution | Directory Open Access Journal |
| issn | 2587-0351 |
| language | English |
| last_indexed | 2024-03-09T07:13:43Z |
| publishDate | 2021-10-01 |
| publisher | Van Yuzuncu Yil University, School of Medicine |
| record_format | Article |
| series | Van Tıp Dergisi |
| spelling | doaj.art-d29a011a76d44b109a3c99c8ac4ceb542023-12-03T08:55:11ZengVan Yuzuncu Yil University, School of MedicineVan Tıp Dergisi2587-03512021-10-0128450250610.5505/vtd.2021.45336VTD-45336Can NLR be Used in Discriminating Simple and Severe Cholecystitis in Emergency Department Admission?Hasan Basri Çetinkaya0Ferhat Çay1Balıkesir University, School Of Medicine, Department Of Emergency Medicine Balıkesir/turkeyBalıkesir University, School Of Medicine, Department Of General Surgery Balıkesir/turkeyINTRODUCTION: Aim: Cholecystitis is a common surgical emergency case, and the progress of simple cholecystitis to severe cholecystitis results in preoperative inflammatory and metabolic complications and a longer hospital stay. We aimed to determine whether the neutrophil-lymphocyte ratio (NLR) could help discriminate between simple and severe cholecystitis in emergency department (ED) admissions. METHODS: Materials and Methods: All patients who were aged 18 or older, were diagnosed with cholecystitis, and presented to ED were included in our retrospective study. Blood laboratory values of patients who were diagnosed with cholecystitis in ED and whose preoperative diagnosis was confirmed were taken. Patients with secondary changes associated with cholecystitis, such as gangrenous cholecystitis and gallbladder perforation, were included in the severe cholecystitis group. RESULTS: Results: The study consisted of 54 patients, including 45 (83.33%) with simple cholecystitis and 9 (16.67%) with severe cholecystitis. Of the 54 patients, 28 (51.85%) were male, 26 (48.15%) were female, and the median age was 71 years (minimum-maximum: 27-94). NLR was found significantly higher in the severe cholecystitis group compared to the simple cholecystitis group (p <0.001). Besides, there was a significant difference between the two groups in terms of CRP, WBC, neutrophil, and lymphocyte values. DISCUSSION AND CONCLUSION: Conclusion: Early discrimination of simple and severe cholecystitis in patients presenting to the emergency department with right upper quadrant pain is important in terms of patient management. We think it may be useful to utilize the NLR ratio to discriminate between simple and severe cholecystitis.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-45336simple cholecystitissevere cholecystitisneutrophil-lymphocyte ratio |
| spellingShingle | Hasan Basri Çetinkaya Ferhat Çay Can NLR be Used in Discriminating Simple and Severe Cholecystitis in Emergency Department Admission? Van Tıp Dergisi simple cholecystitis severe cholecystitis neutrophil-lymphocyte ratio |
| title | Can NLR be Used in Discriminating Simple and Severe Cholecystitis in Emergency Department Admission? |
| title_full | Can NLR be Used in Discriminating Simple and Severe Cholecystitis in Emergency Department Admission? |
| title_fullStr | Can NLR be Used in Discriminating Simple and Severe Cholecystitis in Emergency Department Admission? |
| title_full_unstemmed | Can NLR be Used in Discriminating Simple and Severe Cholecystitis in Emergency Department Admission? |
| title_short | Can NLR be Used in Discriminating Simple and Severe Cholecystitis in Emergency Department Admission? |
| title_sort | can nlr be used in discriminating simple and severe cholecystitis in emergency department admission |
| topic | simple cholecystitis severe cholecystitis neutrophil-lymphocyte ratio |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-45336 |
| work_keys_str_mv | AT hasanbasricetinkaya cannlrbeusedindiscriminatingsimpleandseverecholecystitisinemergencydepartmentadmission AT ferhatcay cannlrbeusedindiscriminatingsimpleandseverecholecystitisinemergencydepartmentadmission |