Frailty score and outcomes of patients undergoing vascular surgery and amputation: A systematic review and meta-analysis
IntroductionFrailty is associated with adverse postoperative health outcomes, including increased mortality, longer length of stay, higher rehospitalization, and other complications. There are many frailty assessment tools are to assess the level of frailty in vascular surgery patients. The aim of t...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1065779/full |
| _version_ | 1828048577552711680 |
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| author | Shujie Chen Riley Dunn Mark Jackson Mark Jackson Nicola Morley Nicola Morley Jing Sun Jing Sun |
| author_facet | Shujie Chen Riley Dunn Mark Jackson Mark Jackson Nicola Morley Nicola Morley Jing Sun Jing Sun |
| author_sort | Shujie Chen |
| collection | DOAJ |
| description | IntroductionFrailty is associated with adverse postoperative health outcomes, including increased mortality, longer length of stay, higher rehospitalization, and other complications. There are many frailty assessment tools are to assess the level of frailty in vascular surgery patients. The aim of this study was to perform a systematic review and meta-analysis to assess the association between the frailty levels described by different frailty scores and adverse postoperative health outcomes among hospitalized vascular surgery patients and patients undergoing amputation.MethodsStudies utilizing frailty scores and similar frailty assessment tools to describe frailty and investigate the association between frailty and health outcomes were searched. The primary outcomes of this study were in-hospital mortality, postdischarge mortality, length of hospital stay, rehospitalization, and discharge location. Additional outcomes included postoperative myocardial infarction, postoperative renal failure, cerebrovascular accident and stroke, comorbidities, and estimated glomerular filtration rate (eGFR) levels. Joanna Briggs Institute (JBI) Critical Appraisal Tools were used for quality assessment.ResultsIn total, 24 studies with 1,886,611 participants were included in the final analysis. The overall results found that higher in-hospital mortality and postdischarge mortality were significantly associated with frailty. Frailty was also found to be significantly associated with a longer length of hospital stay, higher rehospitalization, and higher likelihood of non-home discharge. In addition, the results also showed that frailty was significantly associated with all kinds of comorbidities investigated, except chronic kidney disease. However, lower eGFR levels were significantly associated with frailty.ConclusionAmong patients who underwent all types of vascular surgery and those who underwent amputations, assessment of frailty was significantly associated with adverse postoperative outcomes and multiple comorbidities.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=336374, identifier CRD42022336374. |
| first_indexed | 2024-04-10T18:59:29Z |
| format | Article |
| id | doaj.art-d29af755c27b4879a5f8d6159c52cbb9 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-10T18:59:29Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-d29af755c27b4879a5f8d6159c52cbb92023-01-31T12:41:12ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-01-011010.3389/fcvm.2023.10657791065779Frailty score and outcomes of patients undergoing vascular surgery and amputation: A systematic review and meta-analysisShujie Chen0Riley Dunn1Mark Jackson2Mark Jackson3Nicola Morley4Nicola Morley5Jing Sun6Jing Sun7School of Medicine and Dentistry, Griffith University, Gold Coast, QLD, AustraliaSchool of Pharmacy and Medical Sciences, Griffith University, Nathan, QLD, AustraliaSchool of Medicine and Dentistry, Griffith University, Gold Coast, QLD, AustraliaDepartment of Vascular Surgery, Gold Coast University Hospital, Gold Coast, QLD, AustraliaSchool of Medicine and Dentistry, Griffith University, Gold Coast, QLD, AustraliaDepartment of Vascular Surgery, Gold Coast University Hospital, Gold Coast, QLD, AustraliaSchool of Medicine and Dentistry, Griffith University, Gold Coast, QLD, AustraliaInstitute for Integrated and Intelligent Systems, Griffith University, Gold Coast, QLD, AustraliaIntroductionFrailty is associated with adverse postoperative health outcomes, including increased mortality, longer length of stay, higher rehospitalization, and other complications. There are many frailty assessment tools are to assess the level of frailty in vascular surgery patients. The aim of this study was to perform a systematic review and meta-analysis to assess the association between the frailty levels described by different frailty scores and adverse postoperative health outcomes among hospitalized vascular surgery patients and patients undergoing amputation.MethodsStudies utilizing frailty scores and similar frailty assessment tools to describe frailty and investigate the association between frailty and health outcomes were searched. The primary outcomes of this study were in-hospital mortality, postdischarge mortality, length of hospital stay, rehospitalization, and discharge location. Additional outcomes included postoperative myocardial infarction, postoperative renal failure, cerebrovascular accident and stroke, comorbidities, and estimated glomerular filtration rate (eGFR) levels. Joanna Briggs Institute (JBI) Critical Appraisal Tools were used for quality assessment.ResultsIn total, 24 studies with 1,886,611 participants were included in the final analysis. The overall results found that higher in-hospital mortality and postdischarge mortality were significantly associated with frailty. Frailty was also found to be significantly associated with a longer length of hospital stay, higher rehospitalization, and higher likelihood of non-home discharge. In addition, the results also showed that frailty was significantly associated with all kinds of comorbidities investigated, except chronic kidney disease. However, lower eGFR levels were significantly associated with frailty.ConclusionAmong patients who underwent all types of vascular surgery and those who underwent amputations, assessment of frailty was significantly associated with adverse postoperative outcomes and multiple comorbidities.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=336374, identifier CRD42022336374.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1065779/fullfrailtyfrailty scoresvascular surgeryvascular diseaseamputationshealth outcomes |
| spellingShingle | Shujie Chen Riley Dunn Mark Jackson Mark Jackson Nicola Morley Nicola Morley Jing Sun Jing Sun Frailty score and outcomes of patients undergoing vascular surgery and amputation: A systematic review and meta-analysis Frontiers in Cardiovascular Medicine frailty frailty scores vascular surgery vascular disease amputations health outcomes |
| title | Frailty score and outcomes of patients undergoing vascular surgery and amputation: A systematic review and meta-analysis |
| title_full | Frailty score and outcomes of patients undergoing vascular surgery and amputation: A systematic review and meta-analysis |
| title_fullStr | Frailty score and outcomes of patients undergoing vascular surgery and amputation: A systematic review and meta-analysis |
| title_full_unstemmed | Frailty score and outcomes of patients undergoing vascular surgery and amputation: A systematic review and meta-analysis |
| title_short | Frailty score and outcomes of patients undergoing vascular surgery and amputation: A systematic review and meta-analysis |
| title_sort | frailty score and outcomes of patients undergoing vascular surgery and amputation a systematic review and meta analysis |
| topic | frailty frailty scores vascular surgery vascular disease amputations health outcomes |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1065779/full |
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