Mutations in immunodeficiency-related genes may increase the risk of infection after CAR-T-cell therapy: a report of two cases
Abstract Background Chimeric antigen receptor T-cell therapy (CAR-T) has yielded unprecedented efficacy in B-cell malignancies. With the increasing use of CAR-T-cell therapy, infection has become one of the major concerns after CAR-T-cell infusion. Some patients even develop refractory or recurrent...
Main Authors: | Di Wang, Li He, Chunhui Li, Menglei Xu, Qiuxia Yu, Varlene Daniela Fernandes Almeida, Yimei Que, Yanjie Xu, Yi Xiao, Chunrui Li |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-02-01
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Series: | BMC Infectious Diseases |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12879-023-08070-w |
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