Prevention of violence against women and girls: A cost-effectiveness study across 6 low- and middle-income countries.

<h4>Background</h4>Violence against women and girls (VAWG) is a human rights violation with social, economic, and health consequences for survivors, perpetrators, and society. Robust evidence on economic, social, and health impact, plus the cost of delivery of VAWG prevention, is critica...

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Main Authors: Giulia Ferrari, Sergio Torres-Rueda, Esnat Chirwa, Andrew Gibbs, Stacey Orangi, Edwine Barasa, Theresa Tawiah, Rebecca Kyerewaa Dwommoh Prah, Regis Hitimana, Emmanuelle Daviaud, Eleonah Kapapa, Kristin Dunkle, Lori Heise, Erin Stern, Sangeeta Chatterji, Benjamin Omondi, Deda Ogum Alangea, Rozina Karmaliani, Hussain Maqbool Ahmed Khuwaja, Rachel Jewkes, Charlotte Watts, Anna Vassall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1003827
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author Giulia Ferrari
Sergio Torres-Rueda
Esnat Chirwa
Andrew Gibbs
Stacey Orangi
Edwine Barasa
Theresa Tawiah
Rebecca Kyerewaa Dwommoh Prah
Regis Hitimana
Emmanuelle Daviaud
Eleonah Kapapa
Kristin Dunkle
Lori Heise
Erin Stern
Sangeeta Chatterji
Benjamin Omondi
Deda Ogum Alangea
Rozina Karmaliani
Hussain Maqbool Ahmed Khuwaja
Rachel Jewkes
Charlotte Watts
Anna Vassall
author_facet Giulia Ferrari
Sergio Torres-Rueda
Esnat Chirwa
Andrew Gibbs
Stacey Orangi
Edwine Barasa
Theresa Tawiah
Rebecca Kyerewaa Dwommoh Prah
Regis Hitimana
Emmanuelle Daviaud
Eleonah Kapapa
Kristin Dunkle
Lori Heise
Erin Stern
Sangeeta Chatterji
Benjamin Omondi
Deda Ogum Alangea
Rozina Karmaliani
Hussain Maqbool Ahmed Khuwaja
Rachel Jewkes
Charlotte Watts
Anna Vassall
author_sort Giulia Ferrari
collection DOAJ
description <h4>Background</h4>Violence against women and girls (VAWG) is a human rights violation with social, economic, and health consequences for survivors, perpetrators, and society. Robust evidence on economic, social, and health impact, plus the cost of delivery of VAWG prevention, is critical to making the case for investment, particularly in low- and middle-income countries (LMICs) where health sector resources are highly constrained. We report on the costs and health impact of VAWG prevention in 6 countries.<h4>Methods and findings</h4>We conducted a trial-based cost-effectiveness analysis of VAWG prevention interventions using primary data from 5 randomised controlled trials (RCTs) in sub-Saharan Africa and 1 in South Asia. We evaluated 2 school-based interventions aimed at adolescents (11 to 14 years old) and 2 workshop-based (small group or one to one) interventions, 1 community-based intervention, and 1 combined small group and community-based programme all aimed at adult men and women (18+ years old). All interventions were delivered between 2015 and 2018 and were compared to a do-nothing scenario, except for one of the school-based interventions (government-mandated programme) and for the combined intervention (access to financial services in small groups). We computed the health burden from VAWG with disability-adjusted life year (DALY). We estimated per capita DALYs averted using statistical models that reflect each trial's design and any baseline imbalances. We report cost-effectiveness as cost per DALY averted and characterise uncertainty in the estimates with probabilistic sensitivity analysis (PSA) and cost-effectiveness acceptability curves (CEACs), which show the probability of cost-effectiveness at different thresholds. We report a subgroup analysis of the small group component of the combined intervention and no other subgroup analysis. We also report an impact inventory to illustrate interventions' socioeconomic impact beyond health. We use a 3% discount rate for investment costs and a 1-year time horizon, assuming no effects post the intervention period. From a health sector perspective, the cost per DALY averted varies between US$222 (2018), for an established gender attitudes and harmful social norms change community-based intervention in Ghana, to US$17,548 (2018) for a livelihoods intervention in South Africa. Taking a societal perspective and including wider economic impact improves the cost-effectiveness of some interventions but reduces others. For example, interventions with positive economic impacts, often those with explicit economic goals, offset implementation costs and achieve more favourable cost-effectiveness ratios. Results are robust to sensitivity analyses. Our DALYs include a subset of the health consequences of VAWG exposure; we assume no mortality impact from any of the health consequences included in the DALYs calculations. In both cases, we may be underestimating overall health impact. We also do not report on participants' health costs.<h4>Conclusions</h4>We demonstrate that investment in established community-based VAWG prevention interventions can improve population health in LMICs, even within highly constrained health budgets. However, several VAWG prevention interventions require further modification to achieve affordability and cost-effectiveness at scale. Broadening the range of social, health, and economic outcomes captured in future cost-effectiveness assessments remains critical to justifying the investment urgently required to prevent VAWG globally.
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spelling doaj.art-d29eee2d552d4943976e183d011784ee2022-12-22T02:02:59ZengPublic Library of Science (PLoS)PLoS Medicine1549-12771549-16762022-03-01193e100382710.1371/journal.pmed.1003827Prevention of violence against women and girls: A cost-effectiveness study across 6 low- and middle-income countries.Giulia FerrariSergio Torres-RuedaEsnat ChirwaAndrew GibbsStacey OrangiEdwine BarasaTheresa TawiahRebecca Kyerewaa Dwommoh PrahRegis HitimanaEmmanuelle DaviaudEleonah KapapaKristin DunkleLori HeiseErin SternSangeeta ChatterjiBenjamin OmondiDeda Ogum AlangeaRozina KarmalianiHussain Maqbool Ahmed KhuwajaRachel JewkesCharlotte WattsAnna Vassall<h4>Background</h4>Violence against women and girls (VAWG) is a human rights violation with social, economic, and health consequences for survivors, perpetrators, and society. Robust evidence on economic, social, and health impact, plus the cost of delivery of VAWG prevention, is critical to making the case for investment, particularly in low- and middle-income countries (LMICs) where health sector resources are highly constrained. We report on the costs and health impact of VAWG prevention in 6 countries.<h4>Methods and findings</h4>We conducted a trial-based cost-effectiveness analysis of VAWG prevention interventions using primary data from 5 randomised controlled trials (RCTs) in sub-Saharan Africa and 1 in South Asia. We evaluated 2 school-based interventions aimed at adolescents (11 to 14 years old) and 2 workshop-based (small group or one to one) interventions, 1 community-based intervention, and 1 combined small group and community-based programme all aimed at adult men and women (18+ years old). All interventions were delivered between 2015 and 2018 and were compared to a do-nothing scenario, except for one of the school-based interventions (government-mandated programme) and for the combined intervention (access to financial services in small groups). We computed the health burden from VAWG with disability-adjusted life year (DALY). We estimated per capita DALYs averted using statistical models that reflect each trial's design and any baseline imbalances. We report cost-effectiveness as cost per DALY averted and characterise uncertainty in the estimates with probabilistic sensitivity analysis (PSA) and cost-effectiveness acceptability curves (CEACs), which show the probability of cost-effectiveness at different thresholds. We report a subgroup analysis of the small group component of the combined intervention and no other subgroup analysis. We also report an impact inventory to illustrate interventions' socioeconomic impact beyond health. We use a 3% discount rate for investment costs and a 1-year time horizon, assuming no effects post the intervention period. From a health sector perspective, the cost per DALY averted varies between US$222 (2018), for an established gender attitudes and harmful social norms change community-based intervention in Ghana, to US$17,548 (2018) for a livelihoods intervention in South Africa. Taking a societal perspective and including wider economic impact improves the cost-effectiveness of some interventions but reduces others. For example, interventions with positive economic impacts, often those with explicit economic goals, offset implementation costs and achieve more favourable cost-effectiveness ratios. Results are robust to sensitivity analyses. Our DALYs include a subset of the health consequences of VAWG exposure; we assume no mortality impact from any of the health consequences included in the DALYs calculations. In both cases, we may be underestimating overall health impact. We also do not report on participants' health costs.<h4>Conclusions</h4>We demonstrate that investment in established community-based VAWG prevention interventions can improve population health in LMICs, even within highly constrained health budgets. However, several VAWG prevention interventions require further modification to achieve affordability and cost-effectiveness at scale. Broadening the range of social, health, and economic outcomes captured in future cost-effectiveness assessments remains critical to justifying the investment urgently required to prevent VAWG globally.https://doi.org/10.1371/journal.pmed.1003827
spellingShingle Giulia Ferrari
Sergio Torres-Rueda
Esnat Chirwa
Andrew Gibbs
Stacey Orangi
Edwine Barasa
Theresa Tawiah
Rebecca Kyerewaa Dwommoh Prah
Regis Hitimana
Emmanuelle Daviaud
Eleonah Kapapa
Kristin Dunkle
Lori Heise
Erin Stern
Sangeeta Chatterji
Benjamin Omondi
Deda Ogum Alangea
Rozina Karmaliani
Hussain Maqbool Ahmed Khuwaja
Rachel Jewkes
Charlotte Watts
Anna Vassall
Prevention of violence against women and girls: A cost-effectiveness study across 6 low- and middle-income countries.
PLoS Medicine
title Prevention of violence against women and girls: A cost-effectiveness study across 6 low- and middle-income countries.
title_full Prevention of violence against women and girls: A cost-effectiveness study across 6 low- and middle-income countries.
title_fullStr Prevention of violence against women and girls: A cost-effectiveness study across 6 low- and middle-income countries.
title_full_unstemmed Prevention of violence against women and girls: A cost-effectiveness study across 6 low- and middle-income countries.
title_short Prevention of violence against women and girls: A cost-effectiveness study across 6 low- and middle-income countries.
title_sort prevention of violence against women and girls a cost effectiveness study across 6 low and middle income countries
url https://doi.org/10.1371/journal.pmed.1003827
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