Protein O-GlcNAcylation in multiple immune cells and its therapeutic potential

Protein O-GlcNAcylation in multiple immune cells and its therapeutic potential

O-GlcNAcylation is a post-translational modification of proteins that involves the addition of O-GlcNAc to serine or threonine residues of nuclear or cytoplasmic proteins, catalyzed by O-GlcNAc transferase (OGT). This modification is highly dynamic and can be reversed by O-GlcNAcase (OGA). O-GlcNAcy...

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Bibliographic Details
Main Authors: Huanhuan Cai, Wei Xiong, Haoyan Zhu, Qiongxin Wang, Shi Liu, Zhibing Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
OGT
OGA
O-GlcNAcylation
innate immunity
immune cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1209970/full

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