Impact of PEG sensitization on the efficacy of PEG hydrogel-mediated tissue engineering

Impact of PEG sensitization on the efficacy of PEG hydrogel-mediated tissue engineering

Abstract While poly(ethylene glycol) (PEG) hydrogels are generally regarded as biologically inert blank slates, concerns over PEG immunogenicity are growing, and the implications for tissue engineering are unknown. Here, we investigate these implications by immunizing mice against PEG to stimulate a...

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Bibliographic Details
Main Authors: Alisa H. Isaac, Sarea Y. Recalde Phillips, Elizabeth Ruben, Matthew Estes, Varsha Rajavel, Talia Baig, Carol Paleti, Kirsten Landsgaard, Ryang Hwa Lee, Teja Guda, Michael F. Criscitiello, Carl Gregory, Daniel L. Alge
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46327-3

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