Combined presence of multiple gastrointestinal stromal tumors along with duodenal submucosal somatostatinoma in a patient with neurofibromatosis type 1
Neurofibromatosis type-1 (NF-1) is an autosomal dominant disorder, with increased risk of developing benign and malignant tumors of the gastrointestinal tract (GIT). However, the synchronous presence of multiple GIT stromal tumors and duodenal submucosal somatostatinoma, like in this 50-year-old fem...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=3;spage=359;epage=361;aulast=Kumar |
| _version_ | 1811238328218943488 |
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| author | Tarun Kumar Brijnandan Gupta Prasenjit Das Deepali Jain Hemant Ashok Jain Kumble S Madhusudhan Nihar Ranjan Dash Siddhartha Datta Gupta |
| author_facet | Tarun Kumar Brijnandan Gupta Prasenjit Das Deepali Jain Hemant Ashok Jain Kumble S Madhusudhan Nihar Ranjan Dash Siddhartha Datta Gupta |
| author_sort | Tarun Kumar |
| collection | DOAJ |
| description | Neurofibromatosis type-1 (NF-1) is an autosomal dominant disorder, with increased risk of developing benign and malignant tumors of the gastrointestinal tract (GIT). However, the synchronous presence of multiple GIT stromal tumors and duodenal submucosal somatostatinoma, like in this 50-year-old female NF-1 patient, is very rare. She presented with hematemesis, malena, along with multiple neurofibromas all over the body. Thorough radiological and peroperative work-up revealed multiple ulcerated submucosal and serosal nodules in the proximal small intestine. Histological work-up revealed diagnosis of a duodenal submucosal somatostatinoma with multifocal serosal gastrointestinal stromal tumors. This case is being reported to highlight the rare coincidence of multiple GIT tumors in an NF-1 patient. |
| first_indexed | 2024-04-12T12:39:52Z |
| format | Article |
| id | doaj.art-d2a1c4be1c3b477f820ef308f6da2b2d |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-04-12T12:39:52Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-d2a1c4be1c3b477f820ef308f6da2b2d2022-12-22T03:32:49ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292016-01-0159335936110.4103/0377-4929.188123Combined presence of multiple gastrointestinal stromal tumors along with duodenal submucosal somatostatinoma in a patient with neurofibromatosis type 1Tarun KumarBrijnandan GuptaPrasenjit DasDeepali JainHemant Ashok JainKumble S MadhusudhanNihar Ranjan DashSiddhartha Datta GuptaNeurofibromatosis type-1 (NF-1) is an autosomal dominant disorder, with increased risk of developing benign and malignant tumors of the gastrointestinal tract (GIT). However, the synchronous presence of multiple GIT stromal tumors and duodenal submucosal somatostatinoma, like in this 50-year-old female NF-1 patient, is very rare. She presented with hematemesis, malena, along with multiple neurofibromas all over the body. Thorough radiological and peroperative work-up revealed multiple ulcerated submucosal and serosal nodules in the proximal small intestine. Histological work-up revealed diagnosis of a duodenal submucosal somatostatinoma with multifocal serosal gastrointestinal stromal tumors. This case is being reported to highlight the rare coincidence of multiple GIT tumors in an NF-1 patient.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=3;spage=359;epage=361;aulast=KumarMultiple gastrointestinal stromal tumorsneurofibromatosis type 1periampullary somatostatinoma |
| spellingShingle | Tarun Kumar Brijnandan Gupta Prasenjit Das Deepali Jain Hemant Ashok Jain Kumble S Madhusudhan Nihar Ranjan Dash Siddhartha Datta Gupta Combined presence of multiple gastrointestinal stromal tumors along with duodenal submucosal somatostatinoma in a patient with neurofibromatosis type 1 Indian Journal of Pathology and Microbiology Multiple gastrointestinal stromal tumors neurofibromatosis type 1 periampullary somatostatinoma |
| title | Combined presence of multiple gastrointestinal stromal tumors along with duodenal submucosal somatostatinoma in a patient with neurofibromatosis type 1 |
| title_full | Combined presence of multiple gastrointestinal stromal tumors along with duodenal submucosal somatostatinoma in a patient with neurofibromatosis type 1 |
| title_fullStr | Combined presence of multiple gastrointestinal stromal tumors along with duodenal submucosal somatostatinoma in a patient with neurofibromatosis type 1 |
| title_full_unstemmed | Combined presence of multiple gastrointestinal stromal tumors along with duodenal submucosal somatostatinoma in a patient with neurofibromatosis type 1 |
| title_short | Combined presence of multiple gastrointestinal stromal tumors along with duodenal submucosal somatostatinoma in a patient with neurofibromatosis type 1 |
| title_sort | combined presence of multiple gastrointestinal stromal tumors along with duodenal submucosal somatostatinoma in a patient with neurofibromatosis type 1 |
| topic | Multiple gastrointestinal stromal tumors neurofibromatosis type 1 periampullary somatostatinoma |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=3;spage=359;epage=361;aulast=Kumar |
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