Fecal Microbiota Composition as a Metagenomic Biomarker of Dietary Intake
Gut microbiota encompasses the set of microorganisms that colonize the gastrointestinal tract with mutual relationships that are key for host homeostasis. Increasing evidence supports cross intercommunication between the intestinal microbiome and the eubiosis–dysbiosis binomial, indicating a network...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/5/4918 |
| _version_ | 1797615118497873920 |
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| author | Nathalia Caroline de Oliveira Melo Amanda Cuevas-Sierra Edwin Fernández-Cruz Victor de la O José Alfredo Martínez |
| author_facet | Nathalia Caroline de Oliveira Melo Amanda Cuevas-Sierra Edwin Fernández-Cruz Victor de la O José Alfredo Martínez |
| author_sort | Nathalia Caroline de Oliveira Melo |
| collection | DOAJ |
| description | Gut microbiota encompasses the set of microorganisms that colonize the gastrointestinal tract with mutual relationships that are key for host homeostasis. Increasing evidence supports cross intercommunication between the intestinal microbiome and the eubiosis–dysbiosis binomial, indicating a networking role of gut bacteria as potential metabolic health surrogate markers. The abundance and diversity of the fecal microbial community are already recognized to be associated with several disorders, such as obesity, cardiometabolic events, gastrointestinal alterations, and mental diseases, which suggests that intestinal microbes may be a valuable tool as causal or as consequence biomarkers. In this context, the fecal microbiota could also be used as an adequate and informative proxy of the nutritional composition of the food intake and about the adherence to dietary patterns, such as the Mediterranean or Western diets, by displaying specific fecal microbiome signatures. The aim of this review was to discuss the potential use of gut microbial composition as a putative biomarker of food intake and to screen the sensitivity value of fecal microbiota in the evaluation of dietary interventions as a reliable and precise alternative to subjective questionnaires. |
| first_indexed | 2024-03-11T07:21:58Z |
| format | Article |
| id | doaj.art-d2aedae8cae74a049a07e99e6b85172a |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T07:21:58Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-d2aedae8cae74a049a07e99e6b85172a2023-11-17T07:55:13ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-03-01245491810.3390/ijms24054918Fecal Microbiota Composition as a Metagenomic Biomarker of Dietary IntakeNathalia Caroline de Oliveira Melo0Amanda Cuevas-Sierra1Edwin Fernández-Cruz2Victor de la O3José Alfredo Martínez4IMDEA-Food Institute (Madrid Institute for Advances Studies), Campus of International Excellence (CEI), 28040 Madrid, SpainIMDEA-Food Institute (Madrid Institute for Advances Studies), Campus of International Excellence (CEI), 28040 Madrid, SpainIMDEA-Food Institute (Madrid Institute for Advances Studies), Campus of International Excellence (CEI), 28040 Madrid, SpainIMDEA-Food Institute (Madrid Institute for Advances Studies), Campus of International Excellence (CEI), 28040 Madrid, SpainIMDEA-Food Institute (Madrid Institute for Advances Studies), Campus of International Excellence (CEI), 28040 Madrid, SpainGut microbiota encompasses the set of microorganisms that colonize the gastrointestinal tract with mutual relationships that are key for host homeostasis. Increasing evidence supports cross intercommunication between the intestinal microbiome and the eubiosis–dysbiosis binomial, indicating a networking role of gut bacteria as potential metabolic health surrogate markers. The abundance and diversity of the fecal microbial community are already recognized to be associated with several disorders, such as obesity, cardiometabolic events, gastrointestinal alterations, and mental diseases, which suggests that intestinal microbes may be a valuable tool as causal or as consequence biomarkers. In this context, the fecal microbiota could also be used as an adequate and informative proxy of the nutritional composition of the food intake and about the adherence to dietary patterns, such as the Mediterranean or Western diets, by displaying specific fecal microbiome signatures. The aim of this review was to discuss the potential use of gut microbial composition as a putative biomarker of food intake and to screen the sensitivity value of fecal microbiota in the evaluation of dietary interventions as a reliable and precise alternative to subjective questionnaires.https://www.mdpi.com/1422-0067/24/5/4918biomarkerdietary patternsfidelity measuresfood intakegut microbiotaprecision nutrition |
| spellingShingle | Nathalia Caroline de Oliveira Melo Amanda Cuevas-Sierra Edwin Fernández-Cruz Victor de la O José Alfredo Martínez Fecal Microbiota Composition as a Metagenomic Biomarker of Dietary Intake International Journal of Molecular Sciences biomarker dietary patterns fidelity measures food intake gut microbiota precision nutrition |
| title | Fecal Microbiota Composition as a Metagenomic Biomarker of Dietary Intake |
| title_full | Fecal Microbiota Composition as a Metagenomic Biomarker of Dietary Intake |
| title_fullStr | Fecal Microbiota Composition as a Metagenomic Biomarker of Dietary Intake |
| title_full_unstemmed | Fecal Microbiota Composition as a Metagenomic Biomarker of Dietary Intake |
| title_short | Fecal Microbiota Composition as a Metagenomic Biomarker of Dietary Intake |
| title_sort | fecal microbiota composition as a metagenomic biomarker of dietary intake |
| topic | biomarker dietary patterns fidelity measures food intake gut microbiota precision nutrition |
| url | https://www.mdpi.com/1422-0067/24/5/4918 |
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