Curcumin attenuates prostatic hyperplasia caused by inflammation via up-regulation of bone morphogenetic protein and activin membrane-bound inhibitor

Curcumin attenuates prostatic hyperplasia caused by inflammation via up-regulation of bone morphogenetic protein and activin membrane-bound inhibitor

Context Inflammation and epithelial-mesenchymal transition (EMT) play important roles in the occurrence and development of benign prostatic hyperplasia (BPH); curcumin exerts anti-proliferative, anti-inflammatory, and anti-EMT effects. Objective To explore the anti-inflammatory and anti-EMT mechanis...

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Bibliographic Details
Main Authors: Yuhang Liu, Zhaohui Wang, Yu Gan, Xiang Chen, Bo Zhang, Zhi Chen, Peihuan Liu, Bingsheng Li, Feng Ru, Yao He
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Pharmaceutical Biology
Subjects:
benign prostatic hyperplasia
epithelial-mesenchymal transition
lipopolysaccharide
toll-like receptor 4
tumour necrosis factor-α
Online Access:http://dx.doi.org/10.1080/13880209.2021.1953539

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