Differential richness inference for 16S rRNA marker gene surveys

Differential richness inference for 16S rRNA marker gene surveys

Abstract Background Individual and environmental health outcomes are frequently linked to changes in the diversity of associated microbial communities. Thus, deriving health indicators based on microbiome diversity measures is essential. While microbiome data generated using high-throughput 16S rRNA...

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Bibliographic Details
Main Authors: M. Senthil Kumar, Eric V. Slud, Christine Hehnly, Lijun Zhang, James Broach, Rafael A. Irizarry, Steven J. Schiff, Joseph N. Paulson
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Genome Biology
Subjects:
Microbiome
Spurious
Surveys
False discoveries
Species misclassification
Richness
Online Access:https://doi.org/10.1186/s13059-022-02722-x

Internet

https://doi.org/10.1186/s13059-022-02722-x

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