A two-stage genome-wide association study of radiation-induced acute toxicity in head and neck cancer

A two-stage genome-wide association study of radiation-induced acute toxicity in head and neck cancer

Abstract Background Most head and neck cancer (HNC) patients receive radiotherapy (RT) and develop toxicities. This genome-wide association study (GWAS) was designed to identify single nucleotide polymorphisms (SNPs) associated with common acute radiation-induced toxicities (RITs) in an HNC cohort....

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Bibliographic Details
Main Authors: Elnaz Naderi, Anne Petra Gerarda Crijns, Roel Johannes Henricus Marinus Steenbakkers, Johanna Geertruida Maria van den Hoek, Hendrika Marike Boezen, Behrooz Ziad Alizadeh, Johannes Albertus Langendijk
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Journal of Translational Medicine
Subjects:
Radiogenomics
GWAS
Radiation-induced toxicity
Head and neck cancer
Online Access:https://doi.org/10.1186/s12967-021-03145-1

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