Integrating network pharmacology and experimental validation to clarify the anti-hyperuricemia mechanism of cortex phellodendri in mice

Integrating network pharmacology and experimental validation to clarify the anti-hyperuricemia mechanism of cortex phellodendri in mice

Hyperuricemia (HUA), a common metabolic disease, is treated as the second-largest metabolic disease after diabetes in China. Cortex Phellodendri (CP) is one of the most frequently used herbal medicines for treating gout or HUA. However, the mechanism underlying the anti-HUA effect of CP is still unr...

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Bibliographic Details
Main Authors:	Lieqiang Xu, Juanjuan Cheng, Jieyi Lu, Guoshu Lin, Qiuxia Yu, Yucui Li, Jiannan Chen, Jianhui Xie, Ziren Su, Qi Zhou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Series:	Frontiers in Pharmacology
Subjects:	Cortex Phellodendri hyperuricemia network pharmacology berberine xanthine oxidase
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.964593/full

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