Application of aptamers in regenerative medicine
Regenerative medicine is a discipline that studies how to use biological and engineering principles and operation methods to repair and regenerate damaged tissues and organs. Until now, regenerative medicine has focused mainly on the in-depth study of the pathological mechanism of diseases, the furt...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-08-01
|
| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2022.976960/full |
| _version_ | 1817996159744999424 |
|---|---|
| author | Zhaohui Luo Zhaohui Luo Shimin Chen Shimin Chen Jing Zhou Chong Wang Kai Li Jia Liu Yujin Tang Liqiang Wang |
| author_facet | Zhaohui Luo Zhaohui Luo Shimin Chen Shimin Chen Jing Zhou Chong Wang Kai Li Jia Liu Yujin Tang Liqiang Wang |
| author_sort | Zhaohui Luo |
| collection | DOAJ |
| description | Regenerative medicine is a discipline that studies how to use biological and engineering principles and operation methods to repair and regenerate damaged tissues and organs. Until now, regenerative medicine has focused mainly on the in-depth study of the pathological mechanism of diseases, the further development and application of new drugs, and tissue engineering technology strategies. The emergence of aptamers has supplemented the development methods and types of new drugs and enriched the application elements of tissue engineering technology, injecting new vitality into regenerative medicine. The role and application status of aptamers screened in recent years in various tissue regeneration and repair are reviewed, and the prospects and challenges of aptamer technology are discussed, providing a basis for the design and application of aptamers in long-term transformation. |
| first_indexed | 2024-04-14T02:18:05Z |
| format | Article |
| id | doaj.art-d2b80739fe364bc988642362007bafe8 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-14T02:18:05Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-d2b80739fe364bc988642362007bafe82022-12-22T02:18:08ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852022-08-011010.3389/fbioe.2022.976960976960Application of aptamers in regenerative medicineZhaohui Luo0Zhaohui Luo1Shimin Chen2Shimin Chen3Jing Zhou4Chong Wang5Kai Li6Jia Liu7Yujin Tang8Liqiang Wang9Youjiang Medical University for Nationalities, Baise, Guangxi, ChinaGuangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, ChinaGuangxi Botanical Garden of Medicinal Plants, Nanning, ChinaDalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, ChinaYoujiang Medical University for Nationalities, Baise, Guangxi, ChinaSchool of Mechanical Engineering, Dongguan University of Technology, Dongguan, Guangdong, ChinaAcademy of Orthopedics, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, ChinaGuangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, ChinaGuangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, ChinaState Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai, ChinaRegenerative medicine is a discipline that studies how to use biological and engineering principles and operation methods to repair and regenerate damaged tissues and organs. Until now, regenerative medicine has focused mainly on the in-depth study of the pathological mechanism of diseases, the further development and application of new drugs, and tissue engineering technology strategies. The emergence of aptamers has supplemented the development methods and types of new drugs and enriched the application elements of tissue engineering technology, injecting new vitality into regenerative medicine. The role and application status of aptamers screened in recent years in various tissue regeneration and repair are reviewed, and the prospects and challenges of aptamer technology are discussed, providing a basis for the design and application of aptamers in long-term transformation.https://www.frontiersin.org/articles/10.3389/fbioe.2022.976960/fullaptamertissue regenerationregenerative medicinerepair of tissue injurytransformation and application |
| spellingShingle | Zhaohui Luo Zhaohui Luo Shimin Chen Shimin Chen Jing Zhou Chong Wang Kai Li Jia Liu Yujin Tang Liqiang Wang Application of aptamers in regenerative medicine Frontiers in Bioengineering and Biotechnology aptamer tissue regeneration regenerative medicine repair of tissue injury transformation and application |
| title | Application of aptamers in regenerative medicine |
| title_full | Application of aptamers in regenerative medicine |
| title_fullStr | Application of aptamers in regenerative medicine |
| title_full_unstemmed | Application of aptamers in regenerative medicine |
| title_short | Application of aptamers in regenerative medicine |
| title_sort | application of aptamers in regenerative medicine |
| topic | aptamer tissue regeneration regenerative medicine repair of tissue injury transformation and application |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2022.976960/full |
| work_keys_str_mv | AT zhaohuiluo applicationofaptamersinregenerativemedicine AT zhaohuiluo applicationofaptamersinregenerativemedicine AT shiminchen applicationofaptamersinregenerativemedicine AT shiminchen applicationofaptamersinregenerativemedicine AT jingzhou applicationofaptamersinregenerativemedicine AT chongwang applicationofaptamersinregenerativemedicine AT kaili applicationofaptamersinregenerativemedicine AT jialiu applicationofaptamersinregenerativemedicine AT yujintang applicationofaptamersinregenerativemedicine AT liqiangwang applicationofaptamersinregenerativemedicine |