Interleukin‐23 Secreted by Activated Macrophages Drives γδT Cell Production of Interleukin‐17 to Aggravate Secondary Injury After Intracerebral Hemorrhage

Interleukin‐23 Secreted by Activated Macrophages Drives γδT Cell Production of Interleukin‐17 to Aggravate Secondary Injury After Intracerebral Hemorrhage

BackgroundNeuroinflammation plays a key role in intracerebral hemorrhage (ICH)–induced secondary brain injury, but the specific roles of peripheral inflammatory cells such as macrophages and lymphocytes remain unknown. The purpose of this study was to explore the roles of macrophages, T lymphocytes,...

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Bibliographic Details
Main Authors: Qi Zhong, Kai Zhou, Qiao‐Li Liang, Sen Lin, Yan‐Chun Wang, Xiao‐Yi Xiong, Zhao‐You Meng, Ting Zhao, Wen‐Yao Zhu, Yuan‐Rui Yang, Mao‐Fan Liao, Qiu‐Wen Gong, Liang Liu, Ao Xiong, Junwei Hao, Jian Wang, Qing‐Wu Yang
Format: Article
Language:English
Published: Wiley 2016-10-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
IL‐17
IL‐23
intracerebral hemorrhage
lymphocyte
macrophage
TLR2
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.004340

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