The dietary treatment of histamine intolerance reduces the abundance of some histamine-secreting bacteria of the gut microbiota in histamine intolerant women. A pilot study
Restrictive diets for the treatment of different gastrointestinal disorders are reported to change the composition of intestinal microbiota. Recently, it has been proposed that individuals with histamine intolerance suffer from intestinal dysbiosis, having an overabundance of histamine-secreting bac...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.1018463/full |
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| author | Sònia Sánchez-Pérez Sònia Sánchez-Pérez Sònia Sánchez-Pérez Oriol Comas-Basté Oriol Comas-Basté Oriol Comas-Basté Adriana Duelo Adriana Duelo Adriana Duelo M. Teresa Veciana-Nogués M. Teresa Veciana-Nogués M. Teresa Veciana-Nogués Mercedes Berlanga M. Carmen Vidal-Carou M. Carmen Vidal-Carou M. Carmen Vidal-Carou M. Luz Latorre-Moratalla M. Luz Latorre-Moratalla M. Luz Latorre-Moratalla |
| author_facet | Sònia Sánchez-Pérez Sònia Sánchez-Pérez Sònia Sánchez-Pérez Oriol Comas-Basté Oriol Comas-Basté Oriol Comas-Basté Adriana Duelo Adriana Duelo Adriana Duelo M. Teresa Veciana-Nogués M. Teresa Veciana-Nogués M. Teresa Veciana-Nogués Mercedes Berlanga M. Carmen Vidal-Carou M. Carmen Vidal-Carou M. Carmen Vidal-Carou M. Luz Latorre-Moratalla M. Luz Latorre-Moratalla M. Luz Latorre-Moratalla |
| author_sort | Sònia Sánchez-Pérez |
| collection | DOAJ |
| description | Restrictive diets for the treatment of different gastrointestinal disorders are reported to change the composition of intestinal microbiota. Recently, it has been proposed that individuals with histamine intolerance suffer from intestinal dysbiosis, having an overabundance of histamine-secreting bacteria, but how it is still unknown this state is affected by the usual dietary treatment of histamine intolerance [i.e., low-histamine diet and the supplementation with diamine oxidase (DAO) enzyme]. Thus, a preliminary study was carried out aiming to evaluate the potential changes on the composition of the intestinal microbiota in a group of five women diagnosed with histamine intolerance undergoing 9 months of the dietary treatment of histamine intolerance. After sequencing bacterial 16S rRNA genes (V3-V4 region) and analyzing the data using the EzBioCloud Database, we observed a reduction in certain histamine-secreting bacteria, including the genera Proteus and Raoultella and the specie Proteus mirabilis. Moreover, it was also observed an increase in Roseburia spp., a bacterial group frequently related to gut health. These changes could help to explain the clinical improvement experienced by histamine intolerant women underwent a dietary treatment. |
| first_indexed | 2024-04-11T08:35:52Z |
| format | Article |
| id | doaj.art-d2bd94469ed141138ac94a576d4d498e |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-04-11T08:35:52Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-d2bd94469ed141138ac94a576d4d498e2022-12-22T04:34:19ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-10-01910.3389/fnut.2022.10184631018463The dietary treatment of histamine intolerance reduces the abundance of some histamine-secreting bacteria of the gut microbiota in histamine intolerant women. A pilot studySònia Sánchez-Pérez0Sònia Sánchez-Pérez1Sònia Sánchez-Pérez2Oriol Comas-Basté3Oriol Comas-Basté4Oriol Comas-Basté5Adriana Duelo6Adriana Duelo7Adriana Duelo8M. Teresa Veciana-Nogués9M. Teresa Veciana-Nogués10M. Teresa Veciana-Nogués11Mercedes Berlanga12M. Carmen Vidal-Carou13M. Carmen Vidal-Carou14M. Carmen Vidal-Carou15M. Luz Latorre-Moratalla16M. Luz Latorre-Moratalla17M. Luz Latorre-Moratalla18Departament de Nutrició, Ciències de l’Alimentació i Gastronomia, Facultat de Farmàcia i Ciències de l’Alimentació, Campus de l’Alimentació de Torribera, Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainInstitut de Recerca en Nutrició i Seguretat Alimentària (INSA⋅UB), Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainXarxa d’Innovació Alimentària (XIA), Barcelona, SpainDepartament de Nutrició, Ciències de l’Alimentació i Gastronomia, Facultat de Farmàcia i Ciències de l’Alimentació, Campus de l’Alimentació de Torribera, Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainInstitut de Recerca en Nutrició i Seguretat Alimentària (INSA⋅UB), Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainXarxa d’Innovació Alimentària (XIA), Barcelona, SpainDepartament de Nutrició, Ciències de l’Alimentació i Gastronomia, Facultat de Farmàcia i Ciències de l’Alimentació, Campus de l’Alimentació de Torribera, Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainInstitut de Recerca en Nutrició i Seguretat Alimentària (INSA⋅UB), Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainXarxa d’Innovació Alimentària (XIA), Barcelona, SpainDepartament de Nutrició, Ciències de l’Alimentació i Gastronomia, Facultat de Farmàcia i Ciències de l’Alimentació, Campus de l’Alimentació de Torribera, Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainInstitut de Recerca en Nutrició i Seguretat Alimentària (INSA⋅UB), Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainXarxa d’Innovació Alimentària (XIA), Barcelona, SpainDepartament de Biologia, Sanitat i Mediambient, Secció de Microbiologia, Facultat de Farmàcia i Ciències de l’Alimentació, Universitat de Barcelona (UB), Barcelona, SpainDepartament de Nutrició, Ciències de l’Alimentació i Gastronomia, Facultat de Farmàcia i Ciències de l’Alimentació, Campus de l’Alimentació de Torribera, Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainInstitut de Recerca en Nutrició i Seguretat Alimentària (INSA⋅UB), Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainXarxa d’Innovació Alimentària (XIA), Barcelona, SpainDepartament de Nutrició, Ciències de l’Alimentació i Gastronomia, Facultat de Farmàcia i Ciències de l’Alimentació, Campus de l’Alimentació de Torribera, Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainInstitut de Recerca en Nutrició i Seguretat Alimentària (INSA⋅UB), Universitat de Barcelona (UB), Santa Coloma de Gramenet, SpainXarxa d’Innovació Alimentària (XIA), Barcelona, SpainRestrictive diets for the treatment of different gastrointestinal disorders are reported to change the composition of intestinal microbiota. Recently, it has been proposed that individuals with histamine intolerance suffer from intestinal dysbiosis, having an overabundance of histamine-secreting bacteria, but how it is still unknown this state is affected by the usual dietary treatment of histamine intolerance [i.e., low-histamine diet and the supplementation with diamine oxidase (DAO) enzyme]. Thus, a preliminary study was carried out aiming to evaluate the potential changes on the composition of the intestinal microbiota in a group of five women diagnosed with histamine intolerance undergoing 9 months of the dietary treatment of histamine intolerance. After sequencing bacterial 16S rRNA genes (V3-V4 region) and analyzing the data using the EzBioCloud Database, we observed a reduction in certain histamine-secreting bacteria, including the genera Proteus and Raoultella and the specie Proteus mirabilis. Moreover, it was also observed an increase in Roseburia spp., a bacterial group frequently related to gut health. These changes could help to explain the clinical improvement experienced by histamine intolerant women underwent a dietary treatment.https://www.frontiersin.org/articles/10.3389/fnut.2022.1018463/fullhistamine intoleranceintestinal microbiotagut dysbiosislow-histamine dietDAO supplementationhistamine-secreting bacteria |
| spellingShingle | Sònia Sánchez-Pérez Sònia Sánchez-Pérez Sònia Sánchez-Pérez Oriol Comas-Basté Oriol Comas-Basté Oriol Comas-Basté Adriana Duelo Adriana Duelo Adriana Duelo M. Teresa Veciana-Nogués M. Teresa Veciana-Nogués M. Teresa Veciana-Nogués Mercedes Berlanga M. Carmen Vidal-Carou M. Carmen Vidal-Carou M. Carmen Vidal-Carou M. Luz Latorre-Moratalla M. Luz Latorre-Moratalla M. Luz Latorre-Moratalla The dietary treatment of histamine intolerance reduces the abundance of some histamine-secreting bacteria of the gut microbiota in histamine intolerant women. A pilot study Frontiers in Nutrition histamine intolerance intestinal microbiota gut dysbiosis low-histamine diet DAO supplementation histamine-secreting bacteria |
| title | The dietary treatment of histamine intolerance reduces the abundance of some histamine-secreting bacteria of the gut microbiota in histamine intolerant women. A pilot study |
| title_full | The dietary treatment of histamine intolerance reduces the abundance of some histamine-secreting bacteria of the gut microbiota in histamine intolerant women. A pilot study |
| title_fullStr | The dietary treatment of histamine intolerance reduces the abundance of some histamine-secreting bacteria of the gut microbiota in histamine intolerant women. A pilot study |
| title_full_unstemmed | The dietary treatment of histamine intolerance reduces the abundance of some histamine-secreting bacteria of the gut microbiota in histamine intolerant women. A pilot study |
| title_short | The dietary treatment of histamine intolerance reduces the abundance of some histamine-secreting bacteria of the gut microbiota in histamine intolerant women. A pilot study |
| title_sort | dietary treatment of histamine intolerance reduces the abundance of some histamine secreting bacteria of the gut microbiota in histamine intolerant women a pilot study |
| topic | histamine intolerance intestinal microbiota gut dysbiosis low-histamine diet DAO supplementation histamine-secreting bacteria |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2022.1018463/full |
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