Functional Implications of Active N6-Methyladenosine in Plants
N6-methyladenosine (m6A) is the most common type of eukaryotic mRNA modification and has been found in many organisms, including mammals, and plants. It has important regulatory effects on RNA splicing, export, stability, and translation. The abundance of m6A on RNA depends on the dynamic regulation...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-04-01
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| Series: | Frontiers in Cell and Developmental Biology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fcell.2020.00291/full |
| _version_ | 1818508768713900032 |
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| author | Hongxiang Zheng Simin Li Xiansheng Zhang Na Sui |
| author_facet | Hongxiang Zheng Simin Li Xiansheng Zhang Na Sui |
| author_sort | Hongxiang Zheng |
| collection | DOAJ |
| description | N6-methyladenosine (m6A) is the most common type of eukaryotic mRNA modification and has been found in many organisms, including mammals, and plants. It has important regulatory effects on RNA splicing, export, stability, and translation. The abundance of m6A on RNA depends on the dynamic regulation between methyltransferase (“writer”) and demethylase (“eraser”), and m6A binding protein (“reader”) exerts more specific regulatory function by binding m6A modification sites on RNA. Progress in research has revealed important functions of m6A modification in plants. In this review, we systematically summarize the latest advances in research on the composition and mechanism of action of the m6A system in plants. We emphasize the function of m6A modification on RNA fate, plant development, and stress resistance. Finally, we discuss the outstanding questions and opportunities exist for future research on m6A modification in plant. |
| first_indexed | 2024-12-10T22:36:29Z |
| format | Article |
| id | doaj.art-d2be720e727c4f599585065263128fd0 |
| institution | Directory Open Access Journal |
| issn | 2296-634X |
| language | English |
| last_indexed | 2024-12-10T22:36:29Z |
| publishDate | 2020-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj.art-d2be720e727c4f599585065263128fd02022-12-22T01:30:53ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2020-04-01810.3389/fcell.2020.00291524817Functional Implications of Active N6-Methyladenosine in PlantsHongxiang Zheng0Simin Li1Xiansheng Zhang2Na Sui3Shandong Provincial Key Laboratory of Plant Stress, College of Life Sciences, Shandong Normal University, Jinan, ChinaShandong Provincial Key Laboratory of Plant Stress, College of Life Sciences, Shandong Normal University, Jinan, ChinaState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai’an, ChinaShandong Provincial Key Laboratory of Plant Stress, College of Life Sciences, Shandong Normal University, Jinan, ChinaN6-methyladenosine (m6A) is the most common type of eukaryotic mRNA modification and has been found in many organisms, including mammals, and plants. It has important regulatory effects on RNA splicing, export, stability, and translation. The abundance of m6A on RNA depends on the dynamic regulation between methyltransferase (“writer”) and demethylase (“eraser”), and m6A binding protein (“reader”) exerts more specific regulatory function by binding m6A modification sites on RNA. Progress in research has revealed important functions of m6A modification in plants. In this review, we systematically summarize the latest advances in research on the composition and mechanism of action of the m6A system in plants. We emphasize the function of m6A modification on RNA fate, plant development, and stress resistance. Finally, we discuss the outstanding questions and opportunities exist for future research on m6A modification in plant.https://www.frontiersin.org/article/10.3389/fcell.2020.00291/fullN6-methyladenosinefunctional implicationsplantRNA functionstress response |
| spellingShingle | Hongxiang Zheng Simin Li Xiansheng Zhang Na Sui Functional Implications of Active N6-Methyladenosine in Plants Frontiers in Cell and Developmental Biology N6-methyladenosine functional implications plant RNA function stress response |
| title | Functional Implications of Active N6-Methyladenosine in Plants |
| title_full | Functional Implications of Active N6-Methyladenosine in Plants |
| title_fullStr | Functional Implications of Active N6-Methyladenosine in Plants |
| title_full_unstemmed | Functional Implications of Active N6-Methyladenosine in Plants |
| title_short | Functional Implications of Active N6-Methyladenosine in Plants |
| title_sort | functional implications of active n6 methyladenosine in plants |
| topic | N6-methyladenosine functional implications plant RNA function stress response |
| url | https://www.frontiersin.org/article/10.3389/fcell.2020.00291/full |
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