The impact of anabolic androgenic steroids abuse and type of training on left ventricular remodeling and function in competitive athletes
Background/Aim. Long-term intensive training is associated with distinctive cardiac adaptations which are known as athlete’s heart. The aim of this study was to determine whether the use of anabolic androgenic steroids (AAS) could affect echocardiographic parameters of left ventricular (LV)...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defence, Serbia
2014-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501300046I.pdf |
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| author | Ilić Ivan Đorđević Vitomir Stanković Ivan Vlahović-Stipac Alja Putniković Biljana Babić Rade Nešković Aleksandar N. |
| author_facet | Ilić Ivan Đorđević Vitomir Stanković Ivan Vlahović-Stipac Alja Putniković Biljana Babić Rade Nešković Aleksandar N. |
| author_sort | Ilić Ivan |
| collection | DOAJ |
| description | Background/Aim. Long-term intensive training is associated with distinctive
cardiac adaptations which are known as athlete’s heart. The aim of this study
was to determine whether the use of anabolic androgenic steroids (AAS) could
affect echocardiographic parameters of left ventricular (LV) morphology and
function in elite strength and endurance athletes. Methods. A total of 20
elite strength athletes (10 AAS users and 10 non-users) were compared to 12
steroid-free endurance athletes. All the subjects underwent comprehensive
standard echocardiography and tissue Doppler imaging. Results. After being
indexed for body surface area, both left atrium (LA) and LV end-diastolic
diameter (LVEDD) were significantly higher in the endurance than strength
athletes, regardless of AAS use (p < 0.05, for both). A significant
correlation was found between LA diameter and LVEDD in the steroid-free
endurance athletes, showing that 75% of LA size variability depends on
variability of LVEDD (p < 0.001). No significant differences in ejection
fraction and cardiac output were observed among the groups, although mildly
reduced LV ejection fraction was seen only in the AAS users. The AAS-using
strength athletes had higher A-peak velocity when compared to steroidfree
athletes, regardless of training type (p < 0.05 for both). Both AAS-using and
AAS-free strength athletes had lower e’ peak velocity and higher E/e’ ratio
than endurance athletes (p < 0.05, for all). Conclusions. There is no
evidence that LV ejection fraction in elite athletes is altered by either
type of training or AAS misuse. Long-term endurance training is associated
with preferable effects on LV diastolic function compared to strength
training, particularly when the latter is combined with AAS abuse. |
| first_indexed | 2024-12-23T21:08:15Z |
| format | Article |
| id | doaj.art-d2c0f980ca344afab1e47c5d308678eb |
| institution | Directory Open Access Journal |
| issn | 0042-8450 |
| language | English |
| last_indexed | 2025-03-14T13:08:24Z |
| publishDate | 2014-01-01 |
| publisher | Military Health Department, Ministry of Defence, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-d2c0f980ca344afab1e47c5d308678eb2025-03-02T00:13:07ZengMilitary Health Department, Ministry of Defence, SerbiaVojnosanitetski Pregled0042-84502014-01-0171438338910.2298/VSP130504046I0042-84501300046IThe impact of anabolic androgenic steroids abuse and type of training on left ventricular remodeling and function in competitive athletesIlić Ivan0Đorđević Vitomir1Stanković Ivan2Vlahović-Stipac Alja3Putniković Biljana4Babić Rade5Nešković Aleksandar N.6Faculty of Medicine, Clinical Hospital Center Zemun, Department of Cardiology, BelgradeHealth Center Dr. Ristić, BelgradeFaculty of Medicine, Clinical Hospital Center Zemun, Department of Cardiology, BelgradeFaculty of Medicine, Clinical Hospital Center Zemun, Department of Cardiology, BelgradeFaculty of Medicine, Clinical Hospital Center Zemun, Department of Cardiology, BelgradeDedinje Cardiovascular Institute, BelgradeFaculty of Medicine, Clinical Hospital Center Zemun, Department of Cardiology, BelgradeBackground/Aim. Long-term intensive training is associated with distinctive cardiac adaptations which are known as athlete’s heart. The aim of this study was to determine whether the use of anabolic androgenic steroids (AAS) could affect echocardiographic parameters of left ventricular (LV) morphology and function in elite strength and endurance athletes. Methods. A total of 20 elite strength athletes (10 AAS users and 10 non-users) were compared to 12 steroid-free endurance athletes. All the subjects underwent comprehensive standard echocardiography and tissue Doppler imaging. Results. After being indexed for body surface area, both left atrium (LA) and LV end-diastolic diameter (LVEDD) were significantly higher in the endurance than strength athletes, regardless of AAS use (p < 0.05, for both). A significant correlation was found between LA diameter and LVEDD in the steroid-free endurance athletes, showing that 75% of LA size variability depends on variability of LVEDD (p < 0.001). No significant differences in ejection fraction and cardiac output were observed among the groups, although mildly reduced LV ejection fraction was seen only in the AAS users. The AAS-using strength athletes had higher A-peak velocity when compared to steroidfree athletes, regardless of training type (p < 0.05 for both). Both AAS-using and AAS-free strength athletes had lower e’ peak velocity and higher E/e’ ratio than endurance athletes (p < 0.05, for all). Conclusions. There is no evidence that LV ejection fraction in elite athletes is altered by either type of training or AAS misuse. Long-term endurance training is associated with preferable effects on LV diastolic function compared to strength training, particularly when the latter is combined with AAS abuse.http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501300046I.pdfathletessubstance-related disordersandrogensventricular remodelingrisk assessmentechocardiography |
| spellingShingle | Ilić Ivan Đorđević Vitomir Stanković Ivan Vlahović-Stipac Alja Putniković Biljana Babić Rade Nešković Aleksandar N. The impact of anabolic androgenic steroids abuse and type of training on left ventricular remodeling and function in competitive athletes Vojnosanitetski Pregled athletes substance-related disorders androgens ventricular remodeling risk assessment echocardiography |
| title | The impact of anabolic androgenic steroids abuse and type of training on left ventricular remodeling and function in competitive athletes |
| title_full | The impact of anabolic androgenic steroids abuse and type of training on left ventricular remodeling and function in competitive athletes |
| title_fullStr | The impact of anabolic androgenic steroids abuse and type of training on left ventricular remodeling and function in competitive athletes |
| title_full_unstemmed | The impact of anabolic androgenic steroids abuse and type of training on left ventricular remodeling and function in competitive athletes |
| title_short | The impact of anabolic androgenic steroids abuse and type of training on left ventricular remodeling and function in competitive athletes |
| title_sort | impact of anabolic androgenic steroids abuse and type of training on left ventricular remodeling and function in competitive athletes |
| topic | athletes substance-related disorders androgens ventricular remodeling risk assessment echocardiography |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501300046I.pdf |
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