А PROBLEM OF ACUTE KIDNEY INJURY IN CHILDREN TODAY

In this survey of contemporary foreign literature presents the results of recent studies on acute kidney damage in children. Present modern system of stratification by severity degrees ofacute kidney injury and their comparison (RIFLE and AKIN – criteria). For this reason recently there has been a...

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Main Author: O. Lavrenchuk
Format: Article
Language:English
Published: State Institution «Institute of Nephrology NAMS of Ukraine" 2017-08-01
Series:Український Журнал Нефрології та Діалізу
Subjects:
Online Access:https://ukrjnd.com.ua/index.php/journal/article/view/54
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author O. Lavrenchuk
author_facet O. Lavrenchuk
author_sort O. Lavrenchuk
collection DOAJ
description In this survey of contemporary foreign literature presents the results of recent studies on acute kidney damage in children. Present modern system of stratification by severity degrees ofacute kidney injury and their comparison (RIFLE and AKIN – criteria). For this reason recently there has been a great surge of interest in identifying biomarkers ofacute and chronic kidney injury which help to detect early pathological changes in kidneys, to differentiate the injury of different parts of the nephron, to accurately determine the stage of the process, to assess the severity of inflammation and fibrogenesis intensity. The most important new markers which are currently studied include KIM–1, VEGF–А, L–FABP, TGF–b1, NGAL and NAG. This review highlights the results of major recent studies in this area.
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spelling doaj.art-d2c787ad2b0249fd8d319dacdc8ba9842024-03-15T12:22:56ZengState Institution «Institute of Nephrology NAMS of Ukraine"Український Журнал Нефрології та Діалізу2304-02382616-73522017-08-014(56)10.31450/ukrjnd.4(56).2017.0454А PROBLEM OF ACUTE KIDNEY INJURY IN CHILDREN TODAYO. Lavrenchuk0SI “Institute of Nephrology NAMSof Ukraine” In this survey of contemporary foreign literature presents the results of recent studies on acute kidney damage in children. Present modern system of stratification by severity degrees ofacute kidney injury and their comparison (RIFLE and AKIN – criteria). For this reason recently there has been a great surge of interest in identifying biomarkers ofacute and chronic kidney injury which help to detect early pathological changes in kidneys, to differentiate the injury of different parts of the nephron, to accurately determine the stage of the process, to assess the severity of inflammation and fibrogenesis intensity. The most important new markers which are currently studied include KIM–1, VEGF–А, L–FABP, TGF–b1, NGAL and NAG. This review highlights the results of major recent studies in this area. https://ukrjnd.com.ua/index.php/journal/article/view/54aquite kidney injury, children, clasification, epidemiology, biomarkers of kidney injury, KIM-1, VEGF-А, L-FABP, TGF-b1, NGAL, NAG
spellingShingle O. Lavrenchuk
А PROBLEM OF ACUTE KIDNEY INJURY IN CHILDREN TODAY
Український Журнал Нефрології та Діалізу
aquite kidney injury, children, clasification, epidemiology, biomarkers of kidney injury, KIM-1, VEGF-А, L-FABP, TGF-b1, NGAL, NAG
title А PROBLEM OF ACUTE KIDNEY INJURY IN CHILDREN TODAY
title_full А PROBLEM OF ACUTE KIDNEY INJURY IN CHILDREN TODAY
title_fullStr А PROBLEM OF ACUTE KIDNEY INJURY IN CHILDREN TODAY
title_full_unstemmed А PROBLEM OF ACUTE KIDNEY INJURY IN CHILDREN TODAY
title_short А PROBLEM OF ACUTE KIDNEY INJURY IN CHILDREN TODAY
title_sort а problem of acute kidney injury in children today
topic aquite kidney injury, children, clasification, epidemiology, biomarkers of kidney injury, KIM-1, VEGF-А, L-FABP, TGF-b1, NGAL, NAG
url https://ukrjnd.com.ua/index.php/journal/article/view/54
work_keys_str_mv AT olavrenchuk aproblemofacutekidneyinjuryinchildrentoday