Novel Intraoperative Imaging of Gastric Tube Perfusion during Oncologic Esophagectomy—A Pilot Study Comparing Hyperspectral Imaging (HSI) and Fluorescence Imaging (FI) with Indocyanine Green (ICG)
Background: Novel intraoperative imaging techniques, namely, hyperspectral (HSI) and fluorescence imaging (FI), are promising with respect to reducing severe postoperative complications, thus increasing patient safety. Both tools have already been used to evaluate perfusion of the gastric conduit af...
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MDPI AG
2021-12-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/14/1/97 |
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| author | Sebastian Hennig Boris Jansen-Winkeln Hannes Köhler Luise Knospe Claire Chalopin Marianne Maktabi Annekatrin Pfahl Jana Hoffmann Stefan Kwast Ines Gockel Yusef Moulla |
| author_facet | Sebastian Hennig Boris Jansen-Winkeln Hannes Köhler Luise Knospe Claire Chalopin Marianne Maktabi Annekatrin Pfahl Jana Hoffmann Stefan Kwast Ines Gockel Yusef Moulla |
| author_sort | Sebastian Hennig |
| collection | DOAJ |
| description | Background: Novel intraoperative imaging techniques, namely, hyperspectral (HSI) and fluorescence imaging (FI), are promising with respect to reducing severe postoperative complications, thus increasing patient safety. Both tools have already been used to evaluate perfusion of the gastric conduit after esophagectomy and before anastomosis. To our knowledge, this is the first study evaluating both modalities simultaneously during esophagectomy. Methods: In our pilot study, 13 patients, who underwent Ivor Lewis esophagectomy and gastric conduit reconstruction, were analyzed prospectively. HSI and FI were recorded before establishing the anastomosis in order to determine its optimum position. Results: No anastomotic leak occurred during this pilot study. In five patients, the imaging methods resulted in a more peripheral adaptation of the anastomosis. There were no significant differences between the two imaging tools, and no adverse events due to the imaging methods or indocyanine green (ICG) injection occurred. Conclusions: Simultaneous intraoperative application of both modalities was feasible and not time consuming. They are complementary with regard to the ideal anastomotic position and may contribute to better surgical outcomes. The impact of their simultaneous application will be proven in consecutive prospective trials with a large patient cohort. |
| first_indexed | 2024-03-10T03:47:41Z |
| format | Article |
| id | doaj.art-d2c8db52fbb64d989ddfc8629abc567c |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T03:47:41Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-d2c8db52fbb64d989ddfc8629abc567c2023-11-23T11:16:00ZengMDPI AGCancers2072-66942021-12-011419710.3390/cancers14010097Novel Intraoperative Imaging of Gastric Tube Perfusion during Oncologic Esophagectomy—A Pilot Study Comparing Hyperspectral Imaging (HSI) and Fluorescence Imaging (FI) with Indocyanine Green (ICG)Sebastian Hennig0Boris Jansen-Winkeln1Hannes Köhler2Luise Knospe3Claire Chalopin4Marianne Maktabi5Annekatrin Pfahl6Jana Hoffmann7Stefan Kwast8Ines Gockel9Yusef Moulla10Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Liebigstr. 20, D-04103 Leipzig, GermanyDepartment of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Liebigstr. 20, D-04103 Leipzig, GermanyInnovation Center Computer Assisted Surgery (ICCAS), University of Leipzig, Semmelweisstr. 14, D-04103 Leipzig, GermanyDepartment of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Liebigstr. 20, D-04103 Leipzig, GermanyInnovation Center Computer Assisted Surgery (ICCAS), University of Leipzig, Semmelweisstr. 14, D-04103 Leipzig, GermanyInnovation Center Computer Assisted Surgery (ICCAS), University of Leipzig, Semmelweisstr. 14, D-04103 Leipzig, GermanyInnovation Center Computer Assisted Surgery (ICCAS), University of Leipzig, Semmelweisstr. 14, D-04103 Leipzig, GermanyDepartment of Sports Medicine and Prevention, University Leipzig, Rosa Luxemburg Str. 20-30, D-04103 Leipzig, GermanyDepartment of Sports Medicine and Prevention, University Leipzig, Rosa Luxemburg Str. 20-30, D-04103 Leipzig, GermanyDepartment of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Liebigstr. 20, D-04103 Leipzig, GermanyDepartment of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Liebigstr. 20, D-04103 Leipzig, GermanyBackground: Novel intraoperative imaging techniques, namely, hyperspectral (HSI) and fluorescence imaging (FI), are promising with respect to reducing severe postoperative complications, thus increasing patient safety. Both tools have already been used to evaluate perfusion of the gastric conduit after esophagectomy and before anastomosis. To our knowledge, this is the first study evaluating both modalities simultaneously during esophagectomy. Methods: In our pilot study, 13 patients, who underwent Ivor Lewis esophagectomy and gastric conduit reconstruction, were analyzed prospectively. HSI and FI were recorded before establishing the anastomosis in order to determine its optimum position. Results: No anastomotic leak occurred during this pilot study. In five patients, the imaging methods resulted in a more peripheral adaptation of the anastomosis. There were no significant differences between the two imaging tools, and no adverse events due to the imaging methods or indocyanine green (ICG) injection occurred. Conclusions: Simultaneous intraoperative application of both modalities was feasible and not time consuming. They are complementary with regard to the ideal anastomotic position and may contribute to better surgical outcomes. The impact of their simultaneous application will be proven in consecutive prospective trials with a large patient cohort.https://www.mdpi.com/2072-6694/14/1/97hyperspectral imaging (HSI)fluorescence imaging (FI)indocyanine green (ICG)anastomotic leak (AL)Ivor Lewis esophagectomygastric conduit perfusion |
| spellingShingle | Sebastian Hennig Boris Jansen-Winkeln Hannes Köhler Luise Knospe Claire Chalopin Marianne Maktabi Annekatrin Pfahl Jana Hoffmann Stefan Kwast Ines Gockel Yusef Moulla Novel Intraoperative Imaging of Gastric Tube Perfusion during Oncologic Esophagectomy—A Pilot Study Comparing Hyperspectral Imaging (HSI) and Fluorescence Imaging (FI) with Indocyanine Green (ICG) Cancers hyperspectral imaging (HSI) fluorescence imaging (FI) indocyanine green (ICG) anastomotic leak (AL) Ivor Lewis esophagectomy gastric conduit perfusion |
| title | Novel Intraoperative Imaging of Gastric Tube Perfusion during Oncologic Esophagectomy—A Pilot Study Comparing Hyperspectral Imaging (HSI) and Fluorescence Imaging (FI) with Indocyanine Green (ICG) |
| title_full | Novel Intraoperative Imaging of Gastric Tube Perfusion during Oncologic Esophagectomy—A Pilot Study Comparing Hyperspectral Imaging (HSI) and Fluorescence Imaging (FI) with Indocyanine Green (ICG) |
| title_fullStr | Novel Intraoperative Imaging of Gastric Tube Perfusion during Oncologic Esophagectomy—A Pilot Study Comparing Hyperspectral Imaging (HSI) and Fluorescence Imaging (FI) with Indocyanine Green (ICG) |
| title_full_unstemmed | Novel Intraoperative Imaging of Gastric Tube Perfusion during Oncologic Esophagectomy—A Pilot Study Comparing Hyperspectral Imaging (HSI) and Fluorescence Imaging (FI) with Indocyanine Green (ICG) |
| title_short | Novel Intraoperative Imaging of Gastric Tube Perfusion during Oncologic Esophagectomy—A Pilot Study Comparing Hyperspectral Imaging (HSI) and Fluorescence Imaging (FI) with Indocyanine Green (ICG) |
| title_sort | novel intraoperative imaging of gastric tube perfusion during oncologic esophagectomy a pilot study comparing hyperspectral imaging hsi and fluorescence imaging fi with indocyanine green icg |
| topic | hyperspectral imaging (HSI) fluorescence imaging (FI) indocyanine green (ICG) anastomotic leak (AL) Ivor Lewis esophagectomy gastric conduit perfusion |
| url | https://www.mdpi.com/2072-6694/14/1/97 |
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