Low calf circumference is associated with frailty in diabetic adults aged over 80 years
Abstract Background Frailty is now seen as a significant factor in older people with diabetes, whose mortality and disability increased. This study aims to investigate the association between calf circumference (CC) with frailty in diabetic adults aged over 80 years. Methods A cross-sectional analys...
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| Format: | Article |
| Language: | English |
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BMC
2020-10-01
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| Series: | BMC Geriatrics |
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| Online Access: | http://link.springer.com/article/10.1186/s12877-020-01830-2 |
| _version_ | 1811223468194136064 |
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| author | Yun-Xia Zhu Yue Zhang Yan-Yan Wang Chen-Xi Ren Jun Xu Xiao-Yan Zhang |
| author_facet | Yun-Xia Zhu Yue Zhang Yan-Yan Wang Chen-Xi Ren Jun Xu Xiao-Yan Zhang |
| author_sort | Yun-Xia Zhu |
| collection | DOAJ |
| description | Abstract Background Frailty is now seen as a significant factor in older people with diabetes, whose mortality and disability increased. This study aims to investigate the association between calf circumference (CC) with frailty in diabetic adults aged over 80 years. Methods A cross-sectional analysis was performed on the data of 426 diabetic adults aged over 80 years. On admission, demographic data and laboratory parameters were recorded. CC was measured on the lower right leg at the point of the maximal circumference. All participants accepted frailty assessments. Frailty was mainly defined using the Fried frailty phenotype criteria. Results The CC levels were significantly lower in the frail than the non-frail (26.7 ± 4.0 vs. 31.2 ± 4.0, P < 0.001). CC was negatively correlated with the Fried frailty phenotype index (P < 0.001). Logistic regression analysis of frailty revealed that age (Odds Ratio (OR), 1.368; 95% Confidential Interval (CI) 1.002–1.869; P = 0.049), CC (OR, 0.756; 95%CI 0.598–0.956; P = 0.019) were independent impact factors of frailty after adjusting all the potential confounders. Participants with low CC tertile had a significantly higher Fried frailty phenotype index than those with high CC tertiles. The best CC cut-off value for predicting frailty was 29.3 cm, its sensitivity was 75.0%, and the specificity was 78.6%, and areas under the curve (AUC) was 0.786 (P < 0.001). Conclusions CC was strongly related to frailty in diabetic adults aged over 80 years, suggesting that CC may be helpful for monitoring physical frailty in older adults in clinical and research settings. |
| first_indexed | 2024-04-12T08:33:22Z |
| format | Article |
| id | doaj.art-d2c9666e41c14e69aa1dec4bb2af7d0e |
| institution | Directory Open Access Journal |
| issn | 1471-2318 |
| language | English |
| last_indexed | 2024-04-12T08:33:22Z |
| publishDate | 2020-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj.art-d2c9666e41c14e69aa1dec4bb2af7d0e2022-12-22T03:40:07ZengBMCBMC Geriatrics1471-23182020-10-012011710.1186/s12877-020-01830-2Low calf circumference is associated with frailty in diabetic adults aged over 80 yearsYun-Xia Zhu0Yue Zhang1Yan-Yan Wang2Chen-Xi Ren3Jun Xu4Xiao-Yan Zhang5Department of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People’s HospitalDepartment of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People’s HospitalDepartment of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People’s HospitalDepartment of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People’s HospitalDepartment of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People’s HospitalDepartment of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People’s HospitalAbstract Background Frailty is now seen as a significant factor in older people with diabetes, whose mortality and disability increased. This study aims to investigate the association between calf circumference (CC) with frailty in diabetic adults aged over 80 years. Methods A cross-sectional analysis was performed on the data of 426 diabetic adults aged over 80 years. On admission, demographic data and laboratory parameters were recorded. CC was measured on the lower right leg at the point of the maximal circumference. All participants accepted frailty assessments. Frailty was mainly defined using the Fried frailty phenotype criteria. Results The CC levels were significantly lower in the frail than the non-frail (26.7 ± 4.0 vs. 31.2 ± 4.0, P < 0.001). CC was negatively correlated with the Fried frailty phenotype index (P < 0.001). Logistic regression analysis of frailty revealed that age (Odds Ratio (OR), 1.368; 95% Confidential Interval (CI) 1.002–1.869; P = 0.049), CC (OR, 0.756; 95%CI 0.598–0.956; P = 0.019) were independent impact factors of frailty after adjusting all the potential confounders. Participants with low CC tertile had a significantly higher Fried frailty phenotype index than those with high CC tertiles. The best CC cut-off value for predicting frailty was 29.3 cm, its sensitivity was 75.0%, and the specificity was 78.6%, and areas under the curve (AUC) was 0.786 (P < 0.001). Conclusions CC was strongly related to frailty in diabetic adults aged over 80 years, suggesting that CC may be helpful for monitoring physical frailty in older adults in clinical and research settings.http://link.springer.com/article/10.1186/s12877-020-01830-2Calf circumferenceFrailtyAgingDiabetes |
| spellingShingle | Yun-Xia Zhu Yue Zhang Yan-Yan Wang Chen-Xi Ren Jun Xu Xiao-Yan Zhang Low calf circumference is associated with frailty in diabetic adults aged over 80 years BMC Geriatrics Calf circumference Frailty Aging Diabetes |
| title | Low calf circumference is associated with frailty in diabetic adults aged over 80 years |
| title_full | Low calf circumference is associated with frailty in diabetic adults aged over 80 years |
| title_fullStr | Low calf circumference is associated with frailty in diabetic adults aged over 80 years |
| title_full_unstemmed | Low calf circumference is associated with frailty in diabetic adults aged over 80 years |
| title_short | Low calf circumference is associated with frailty in diabetic adults aged over 80 years |
| title_sort | low calf circumference is associated with frailty in diabetic adults aged over 80 years |
| topic | Calf circumference Frailty Aging Diabetes |
| url | http://link.springer.com/article/10.1186/s12877-020-01830-2 |
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