Matrix Effectors in the Pathogenesis of Keratinocyte-Derived Carcinomas

Matrix Effectors in the Pathogenesis of Keratinocyte-Derived Carcinomas

Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), referred to as keratinocyte carcinomas, are skin cancer with the highest incidence. BCCs, rarely metastasize; whereas, though generally not characterized by high lethality, approximately 2–4% of primary cSCCs metastasize with p...

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Bibliographic Details
Main Authors: Rafaela-Maria Kavasi, Monica Neagu, Carolina Constantin, Adriana Munteanu, Mihaela Surcel, Aristidis Tsatsakis, George N. Tzanakakis, Dragana Nikitovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Medicine
Subjects:
extracellular matrix
hyaluronan
collagen
proteoglycans
metalloproteinases
skin
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.879500/full

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