Teaching reproducible research for medical students and postgraduate pharmaceutical scientists

Abstract In medicine and other academic settings, (doctoral) students often work in interdisciplinary teams together with researchers of pharmaceutical sciences, natural sciences in general, or biostatistics. They should be fundamentally taught good research practices, especially in terms of statist...

Full description

Bibliographic Details
Main Author: Andreas D. Meid
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BMC Research Notes
Subjects:
Online Access:https://doi.org/10.1186/s13104-021-05862-8
_version_ 1818388655849340928
author Andreas D. Meid
author_facet Andreas D. Meid
author_sort Andreas D. Meid
collection DOAJ
description Abstract In medicine and other academic settings, (doctoral) students often work in interdisciplinary teams together with researchers of pharmaceutical sciences, natural sciences in general, or biostatistics. They should be fundamentally taught good research practices, especially in terms of statistical analysis. This includes reproducibility as a central aspect. Acknowledging that even experienced researchers and supervisors might be unfamiliar with necessary aspects of a perfectly reproducible workflow, a lecture series on reproducible research (RR) was developed for young scientists in clinical pharmacology. The pilot series highlighted definitions of RR, reasons for RR, potential merits of RR, and ways to work accordingly. In trying to actually reproduce a published analysis, several practical obstacles arose. In this article, reproduction of a working example is commented to emphasize the manifold facets of RR, to provide possible explanations for difficulties and solutions, and to argue that harmonized curricula for (quantitative) clinical researchers should include RR principles. These experiences should raise awareness among educators and students, supervisors and young scientists. RR working habits are not only beneficial for ourselves or our students, but also for other researchers within an institution, for scientific partners, for the scientific community, and eventually for the public profiting from research findings.
first_indexed 2024-12-14T04:29:18Z
format Article
id doaj.art-d2cd97e113ef4d0e8d84f239817aa2ed
institution Directory Open Access Journal
issn 1756-0500
language English
last_indexed 2024-12-14T04:29:18Z
publishDate 2021-12-01
publisher BMC
record_format Article
series BMC Research Notes
spelling doaj.art-d2cd97e113ef4d0e8d84f239817aa2ed2022-12-21T23:17:08ZengBMCBMC Research Notes1756-05002021-12-011411610.1186/s13104-021-05862-8Teaching reproducible research for medical students and postgraduate pharmaceutical scientistsAndreas D. Meid0Department of Clinical Pharmacology and Pharmacoepidemiology, University of HeidelbergAbstract In medicine and other academic settings, (doctoral) students often work in interdisciplinary teams together with researchers of pharmaceutical sciences, natural sciences in general, or biostatistics. They should be fundamentally taught good research practices, especially in terms of statistical analysis. This includes reproducibility as a central aspect. Acknowledging that even experienced researchers and supervisors might be unfamiliar with necessary aspects of a perfectly reproducible workflow, a lecture series on reproducible research (RR) was developed for young scientists in clinical pharmacology. The pilot series highlighted definitions of RR, reasons for RR, potential merits of RR, and ways to work accordingly. In trying to actually reproduce a published analysis, several practical obstacles arose. In this article, reproduction of a working example is commented to emphasize the manifold facets of RR, to provide possible explanations for difficulties and solutions, and to argue that harmonized curricula for (quantitative) clinical researchers should include RR principles. These experiences should raise awareness among educators and students, supervisors and young scientists. RR working habits are not only beneficial for ourselves or our students, but also for other researchers within an institution, for scientific partners, for the scientific community, and eventually for the public profiting from research findings.https://doi.org/10.1186/s13104-021-05862-8Reproducible researchReproducibilityHeterogeneous treatment effectsMachine learningMedical education
spellingShingle Andreas D. Meid
Teaching reproducible research for medical students and postgraduate pharmaceutical scientists
BMC Research Notes
Reproducible research
Reproducibility
Heterogeneous treatment effects
Machine learning
Medical education
title Teaching reproducible research for medical students and postgraduate pharmaceutical scientists
title_full Teaching reproducible research for medical students and postgraduate pharmaceutical scientists
title_fullStr Teaching reproducible research for medical students and postgraduate pharmaceutical scientists
title_full_unstemmed Teaching reproducible research for medical students and postgraduate pharmaceutical scientists
title_short Teaching reproducible research for medical students and postgraduate pharmaceutical scientists
title_sort teaching reproducible research for medical students and postgraduate pharmaceutical scientists
topic Reproducible research
Reproducibility
Heterogeneous treatment effects
Machine learning
Medical education
url https://doi.org/10.1186/s13104-021-05862-8
work_keys_str_mv AT andreasdmeid teachingreproducibleresearchformedicalstudentsandpostgraduatepharmaceuticalscientists