Effectiveness of the Booster Dose in Protecting against COVID-19, Colombia 2022
Vaccination has proven to be one of the most effective strategies against the COVID-19 pandemic. Several studies have evaluated and confirmed its effectiveness in different populations, particularly in reducing severe outcomes such as hospitalization and death. Some studies have investigated the eff...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-09-01
|
| Series: | Vaccines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/11/9/1461 |
| _version_ | 1797576506732445696 |
|---|---|
| author | Jubby Marcela Gálvez Ángela María Pinzón-Rondón Henry Mauricio Chaparro-Solano Hanna Valentina Tovar-Romero Juliana Ramírez-Prieto Sergio Andrés Ortigoza-Espitia Ángela María Ruiz-Sternberg |
| author_facet | Jubby Marcela Gálvez Ángela María Pinzón-Rondón Henry Mauricio Chaparro-Solano Hanna Valentina Tovar-Romero Juliana Ramírez-Prieto Sergio Andrés Ortigoza-Espitia Ángela María Ruiz-Sternberg |
| author_sort | Jubby Marcela Gálvez |
| collection | DOAJ |
| description | Vaccination has proven to be one of the most effective strategies against the COVID-19 pandemic. Several studies have evaluated and confirmed its effectiveness in different populations, particularly in reducing severe outcomes such as hospitalization and death. Some studies have investigated the effectiveness of vaccination against the infection, identifying the need for booster doses. This study aimed to explore the effectiveness of the vaccination schedule on the probability of infection in a sample of Colombian patients during the fourth wave of the COVID-19 pandemic, which was associated with the emergence and predominance of the Omicron variant. A cross-sectional study was conducted on individuals who underwent RT-PCR testing for COVID-19 detection in a dedicated laboratory in Bogotá, Colombia, between 30 December 2021 and 7 February 2022. A total of 1468 subjects was included in the study, of whom 36.6% (n = 538) had a positive PCR test for COVID-19. The comparison between fully vaccinated individuals with a booster dose and those without the booster dose revealed a 28% reduction in the odds of infection (OR = 0.719 CI 0.531–0.971). Age (OR = 1.009 CI 1.001–1.018) and low economic status (OR = 1.812 CI 1.416–2.319) were associated with an increased risk of infection. These findings suggest the need for a booster vaccination in the general population to improve the prevention rates of SARS-CoV-2 infection and mitigate severe outcomes. |
| first_indexed | 2024-03-10T21:52:57Z |
| format | Article |
| id | doaj.art-d2cdd17ca70a44da8c63ecbd0161a69a |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-10T21:52:57Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-d2cdd17ca70a44da8c63ecbd0161a69a2023-11-19T13:19:17ZengMDPI AGVaccines2076-393X2023-09-01119146110.3390/vaccines11091461Effectiveness of the Booster Dose in Protecting against COVID-19, Colombia 2022Jubby Marcela Gálvez0Ángela María Pinzón-Rondón1Henry Mauricio Chaparro-Solano2Hanna Valentina Tovar-Romero3Juliana Ramírez-Prieto4Sergio Andrés Ortigoza-Espitia5Ángela María Ruiz-Sternberg6Genuino Research Group, Gencell Pharma, Bogotá 111221, ColombiaClinical Investigation Group, Universidad del Rosario, Carrera 24 #63C-69, Bogotá 111221, ColombiaClinical Investigation Group, Universidad del Rosario, Carrera 24 #63C-69, Bogotá 111221, ColombiaClinical Investigation Group, Universidad del Rosario, Carrera 24 #63C-69, Bogotá 111221, ColombiaClinical Investigation Group, Universidad del Rosario, Carrera 24 #63C-69, Bogotá 111221, ColombiaClinical Investigation Group, Universidad del Rosario, Carrera 24 #63C-69, Bogotá 111221, ColombiaClinical Investigation Group, Universidad del Rosario, Carrera 24 #63C-69, Bogotá 111221, ColombiaVaccination has proven to be one of the most effective strategies against the COVID-19 pandemic. Several studies have evaluated and confirmed its effectiveness in different populations, particularly in reducing severe outcomes such as hospitalization and death. Some studies have investigated the effectiveness of vaccination against the infection, identifying the need for booster doses. This study aimed to explore the effectiveness of the vaccination schedule on the probability of infection in a sample of Colombian patients during the fourth wave of the COVID-19 pandemic, which was associated with the emergence and predominance of the Omicron variant. A cross-sectional study was conducted on individuals who underwent RT-PCR testing for COVID-19 detection in a dedicated laboratory in Bogotá, Colombia, between 30 December 2021 and 7 February 2022. A total of 1468 subjects was included in the study, of whom 36.6% (n = 538) had a positive PCR test for COVID-19. The comparison between fully vaccinated individuals with a booster dose and those without the booster dose revealed a 28% reduction in the odds of infection (OR = 0.719 CI 0.531–0.971). Age (OR = 1.009 CI 1.001–1.018) and low economic status (OR = 1.812 CI 1.416–2.319) were associated with an increased risk of infection. These findings suggest the need for a booster vaccination in the general population to improve the prevention rates of SARS-CoV-2 infection and mitigate severe outcomes.https://www.mdpi.com/2076-393X/11/9/1461COVID-19booster doseeffectivenessColombiavaccination strategy |
| spellingShingle | Jubby Marcela Gálvez Ángela María Pinzón-Rondón Henry Mauricio Chaparro-Solano Hanna Valentina Tovar-Romero Juliana Ramírez-Prieto Sergio Andrés Ortigoza-Espitia Ángela María Ruiz-Sternberg Effectiveness of the Booster Dose in Protecting against COVID-19, Colombia 2022 Vaccines COVID-19 booster dose effectiveness Colombia vaccination strategy |
| title | Effectiveness of the Booster Dose in Protecting against COVID-19, Colombia 2022 |
| title_full | Effectiveness of the Booster Dose in Protecting against COVID-19, Colombia 2022 |
| title_fullStr | Effectiveness of the Booster Dose in Protecting against COVID-19, Colombia 2022 |
| title_full_unstemmed | Effectiveness of the Booster Dose in Protecting against COVID-19, Colombia 2022 |
| title_short | Effectiveness of the Booster Dose in Protecting against COVID-19, Colombia 2022 |
| title_sort | effectiveness of the booster dose in protecting against covid 19 colombia 2022 |
| topic | COVID-19 booster dose effectiveness Colombia vaccination strategy |
| url | https://www.mdpi.com/2076-393X/11/9/1461 |
| work_keys_str_mv | AT jubbymarcelagalvez effectivenessoftheboosterdoseinprotectingagainstcovid19colombia2022 AT angelamariapinzonrondon effectivenessoftheboosterdoseinprotectingagainstcovid19colombia2022 AT henrymauriciochaparrosolano effectivenessoftheboosterdoseinprotectingagainstcovid19colombia2022 AT hannavalentinatovarromero effectivenessoftheboosterdoseinprotectingagainstcovid19colombia2022 AT julianaramirezprieto effectivenessoftheboosterdoseinprotectingagainstcovid19colombia2022 AT sergioandresortigozaespitia effectivenessoftheboosterdoseinprotectingagainstcovid19colombia2022 AT angelamariaruizsternberg effectivenessoftheboosterdoseinprotectingagainstcovid19colombia2022 |