Alterations in gut microbiota and metabolite profiles in patients with infantile cholestasis

Alterations in gut microbiota and metabolite profiles in patients with infantile cholestasis

Abstract Background Infantile cholestasis (IC) is the most common hepatobiliary disease in infants, resulting in elevated direct bilirubin levels. Indeed, hepatointestinal circulation impacts bile acid and bilirubin metabolism. This study evaluates changes in the gut microbiota composition in childr...

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Bibliographic Details
Main Authors: Meng Jin, Jinghua Cui, Huijuan Ning, Meijuan Wang, Wenwen Liu, Kunyu Yao, Jing Yuan, Xuemei Zhong
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Microbiology
Subjects:
Infantile cholestasis (IC)
Gut microbiota
Microbiota-derived metabolites
Ruminococcus
Butyrivibrio
Veillonella
Online Access:https://doi.org/10.1186/s12866-023-03115-1

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