Breast Carcinoma Metastasis to Thyroid Gland Masquerading as Nodular Goitre: A Case Report
Thyroid gland, despite being a highly vascular organ, is an extremely unusual site for metastasis from primary carcinoma like breast. We, hereby, report a case of metastatic lesion in the thyroid with breast carcinoma as a primary, in a 55-year-old postmenopausal female. The metastatic focus had m...
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JCDR Research and Publications Private Limited
2023-07-01
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Series: | Journal of Clinical and Diagnostic Research |
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Online Access: | https://www.jcdr.net/articles/PDF/18181/62556_CE[Ra1]_F(IS)_PF(HJ_VI_IS)_PFA(HJ_KM)_PN(KM).pdf |
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author | Anita Nangia Shruti Chauhan |
author_facet | Anita Nangia Shruti Chauhan |
author_sort | Anita Nangia |
collection | DOAJ |
description | Thyroid gland, despite being a highly vascular organ, is an extremely unusual site for metastasis from primary carcinoma like breast.
We, hereby, report a case of metastatic lesion in the thyroid with breast carcinoma as a primary, in a 55-year-old postmenopausal
female. The metastatic focus had masqueraded as nodular goitre, thereby, creating diagnostic difficulty. The case was suspected on
Fine Needle Aspiration (FNA) and confirmed by immunocytochemistry on cell block with progesterone and Her2neu positivity. Also,
we have attempted to review the literature reporting similar occurrences. Although breast cancer is less frequent to metastasize to
thyroid, it is advised to always exclude metastasis from breast carcinoma especially if new thyroid lesions occur in patients with this
malignancy. Such cases create diagnostic dilemma on cytology due to morphologic similarities between primary and metastatic
thyroid lesions. Cell block is a crucial technique where ancillary techniques like immunocytochemistry can be applied and help in
early and timely diagnosis, hence, rendering better prognostic outcome.
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format | Article |
id | doaj.art-d2d3c113c2704c0b9aa786120172a05e |
institution | Directory Open Access Journal |
issn | 2249-782X 0973-709X |
language | English |
last_indexed | 2024-03-12T20:59:24Z |
publishDate | 2023-07-01 |
publisher | JCDR Research and Publications Private Limited |
record_format | Article |
series | Journal of Clinical and Diagnostic Research |
spelling | doaj.art-d2d3c113c2704c0b9aa786120172a05e2023-07-31T11:01:03ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-07-01177101310.7860/JCDR/2023/62556.18181Breast Carcinoma Metastasis to Thyroid Gland Masquerading as Nodular Goitre: A Case ReportAnita Nangia0Shruti Chauhan1Director Professor, Department of Pathology, Lady Hardinge Medical College, Delhi, India.Assistant Professor, Department of Pathology, Lady Hardinge Medical College, Delhi, India.Thyroid gland, despite being a highly vascular organ, is an extremely unusual site for metastasis from primary carcinoma like breast. We, hereby, report a case of metastatic lesion in the thyroid with breast carcinoma as a primary, in a 55-year-old postmenopausal female. The metastatic focus had masqueraded as nodular goitre, thereby, creating diagnostic difficulty. The case was suspected on Fine Needle Aspiration (FNA) and confirmed by immunocytochemistry on cell block with progesterone and Her2neu positivity. Also, we have attempted to review the literature reporting similar occurrences. Although breast cancer is less frequent to metastasize to thyroid, it is advised to always exclude metastasis from breast carcinoma especially if new thyroid lesions occur in patients with this malignancy. Such cases create diagnostic dilemma on cytology due to morphologic similarities between primary and metastatic thyroid lesions. Cell block is a crucial technique where ancillary techniques like immunocytochemistry can be applied and help in early and timely diagnosis, hence, rendering better prognostic outcome. https://www.jcdr.net/articles/PDF/18181/62556_CE[Ra1]_F(IS)_PF(HJ_VI_IS)_PFA(HJ_KM)_PN(KM).pdfbreast carcinomacell blockher 2 neuimmunocytochemistryinvasive ductal carcinoma metastasisprogesteronesynchronousthyroid glan |
spellingShingle | Anita Nangia Shruti Chauhan Breast Carcinoma Metastasis to Thyroid Gland Masquerading as Nodular Goitre: A Case Report Journal of Clinical and Diagnostic Research breast carcinoma cell block her 2 neu immunocytochemistry invasive ductal carcinoma metastasis progesterone synchronous thyroid glan |
title | Breast Carcinoma Metastasis to Thyroid Gland Masquerading as Nodular Goitre: A Case Report |
title_full | Breast Carcinoma Metastasis to Thyroid Gland Masquerading as Nodular Goitre: A Case Report |
title_fullStr | Breast Carcinoma Metastasis to Thyroid Gland Masquerading as Nodular Goitre: A Case Report |
title_full_unstemmed | Breast Carcinoma Metastasis to Thyroid Gland Masquerading as Nodular Goitre: A Case Report |
title_short | Breast Carcinoma Metastasis to Thyroid Gland Masquerading as Nodular Goitre: A Case Report |
title_sort | breast carcinoma metastasis to thyroid gland masquerading as nodular goitre a case report |
topic | breast carcinoma cell block her 2 neu immunocytochemistry invasive ductal carcinoma metastasis progesterone synchronous thyroid glan |
url | https://www.jcdr.net/articles/PDF/18181/62556_CE[Ra1]_F(IS)_PF(HJ_VI_IS)_PFA(HJ_KM)_PN(KM).pdf |
work_keys_str_mv | AT anitanangia breastcarcinomametastasistothyroidglandmasqueradingasnodulargoitreacasereport AT shrutichauhan breastcarcinomametastasistothyroidglandmasqueradingasnodulargoitreacasereport |