Atrial fibrillation in retinal vascular occlusion disease and non-arteritic anterior ischemic optic neuropathy.
Patients with retinal vascular occlusion disease have an increased risk for ischemic stroke and share some risk factors with cerebrovascular disease. The purpose of this study was to analyze the prevalence of atrial fibrillation (AF) in subjects with retinal vascular occlusive disease and anterior i...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5542383?pdf=render |
| _version_ | 1818310787779788800 |
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| author | Josep Callizo Nicolas Feltgen Antje Ammermann Janina Ganser Sebastian Bemme Thomas Bertelmann Sebastian Pfeiffer Andre Duvinage Klaus Gröschel Hans Hoerauf Rolf Wachter |
| author_facet | Josep Callizo Nicolas Feltgen Antje Ammermann Janina Ganser Sebastian Bemme Thomas Bertelmann Sebastian Pfeiffer Andre Duvinage Klaus Gröschel Hans Hoerauf Rolf Wachter |
| author_sort | Josep Callizo |
| collection | DOAJ |
| description | Patients with retinal vascular occlusion disease have an increased risk for ischemic stroke and share some risk factors with cerebrovascular disease. The purpose of this study was to analyze the prevalence of atrial fibrillation (AF) in subjects with retinal vascular occlusive disease and anterior ischemic optic neuropathy and to compare these data to an ischemic stroke group.Prospective, observational single-center trial. Subjects with retinal artery occlusion (RAO), retinal vein occlusion (RVO) and anterior ischemic optic neuropathy (AION) were included. Patients with ischemic stroke (IS) from a previous observational trial were used as control. Investigation included 7-day Holter ECG, echocardiography, duplex ultrasonography of the carotid arteries, and 24-hour blood pressure monitoring. Further vascular risk factors were documented.During the 1-year study period, 101 patients were recruited. The control group with ischemic stroke consisted of 272 subjects. At inclusion, the prevalence of AF was 12% (RAO), 10.2% (RVO), 11.1% (NAION) and 15.8% (IS). The final prevalence after Holter ECG rose to 16% (RAO), 18.4% (RVO), 14.8% (NAION) and 26.5% (IS). No significant difference was measured between groups.We detected a similar prevalence of AF in all groups. RVO patients tended to exhibit a higher AF detection rate and lower number needed to screen than RAO and NAION. The detection of AF rose considerably via Holter ECG. As a consequence, we recommend prolonged ECG monitoring in patients with acute ophthalmic vascular diseases. |
| first_indexed | 2024-12-13T07:51:37Z |
| format | Article |
| id | doaj.art-d2d8266144fa4d4980470a01eda18fa9 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-13T07:51:37Z |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-d2d8266144fa4d4980470a01eda18fa92022-12-21T23:54:39ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01128e018176610.1371/journal.pone.0181766Atrial fibrillation in retinal vascular occlusion disease and non-arteritic anterior ischemic optic neuropathy.Josep CallizoNicolas FeltgenAntje AmmermannJanina GanserSebastian BemmeThomas BertelmannSebastian PfeifferAndre DuvinageKlaus GröschelHans HoeraufRolf WachterPatients with retinal vascular occlusion disease have an increased risk for ischemic stroke and share some risk factors with cerebrovascular disease. The purpose of this study was to analyze the prevalence of atrial fibrillation (AF) in subjects with retinal vascular occlusive disease and anterior ischemic optic neuropathy and to compare these data to an ischemic stroke group.Prospective, observational single-center trial. Subjects with retinal artery occlusion (RAO), retinal vein occlusion (RVO) and anterior ischemic optic neuropathy (AION) were included. Patients with ischemic stroke (IS) from a previous observational trial were used as control. Investigation included 7-day Holter ECG, echocardiography, duplex ultrasonography of the carotid arteries, and 24-hour blood pressure monitoring. Further vascular risk factors were documented.During the 1-year study period, 101 patients were recruited. The control group with ischemic stroke consisted of 272 subjects. At inclusion, the prevalence of AF was 12% (RAO), 10.2% (RVO), 11.1% (NAION) and 15.8% (IS). The final prevalence after Holter ECG rose to 16% (RAO), 18.4% (RVO), 14.8% (NAION) and 26.5% (IS). No significant difference was measured between groups.We detected a similar prevalence of AF in all groups. RVO patients tended to exhibit a higher AF detection rate and lower number needed to screen than RAO and NAION. The detection of AF rose considerably via Holter ECG. As a consequence, we recommend prolonged ECG monitoring in patients with acute ophthalmic vascular diseases.http://europepmc.org/articles/PMC5542383?pdf=render |
| spellingShingle | Josep Callizo Nicolas Feltgen Antje Ammermann Janina Ganser Sebastian Bemme Thomas Bertelmann Sebastian Pfeiffer Andre Duvinage Klaus Gröschel Hans Hoerauf Rolf Wachter Atrial fibrillation in retinal vascular occlusion disease and non-arteritic anterior ischemic optic neuropathy. PLoS ONE |
| title | Atrial fibrillation in retinal vascular occlusion disease and non-arteritic anterior ischemic optic neuropathy. |
| title_full | Atrial fibrillation in retinal vascular occlusion disease and non-arteritic anterior ischemic optic neuropathy. |
| title_fullStr | Atrial fibrillation in retinal vascular occlusion disease and non-arteritic anterior ischemic optic neuropathy. |
| title_full_unstemmed | Atrial fibrillation in retinal vascular occlusion disease and non-arteritic anterior ischemic optic neuropathy. |
| title_short | Atrial fibrillation in retinal vascular occlusion disease and non-arteritic anterior ischemic optic neuropathy. |
| title_sort | atrial fibrillation in retinal vascular occlusion disease and non arteritic anterior ischemic optic neuropathy |
| url | http://europepmc.org/articles/PMC5542383?pdf=render |
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