Angiogenic Function of Human Placental Endothelial Cells in Severe Fetal Growth Restriction Is Not Rescued by Individual Extracellular Matrix Proteins

Angiogenic Function of Human Placental Endothelial Cells in Severe Fetal Growth Restriction Is Not Rescued by Individual Extracellular Matrix Proteins

Severe fetal growth restriction (FGR) is characterized by increased placental vascular resistance resulting from aberrant angiogenesis. Interactions between endothelial cells (ECs) and the extracellular matrix (ECM) are critical to the complex process of angiogenesis. We have previously found that p...

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Bibliographic Details
Main Authors: Lauren Sayres, Amanda R. Flockton, Shuhan Ji, Carla Rey Diaz, Diane L. Gumina, Emily J. Su
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
fetal growth restriction
umbilical artery Dopplers
human placental endothelial cells
extracellular matrix
angiogenesis
Online Access:https://www.mdpi.com/2073-4409/12/19/2339

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