Proteomining-Based Elucidation of Natural Product Biosynthetic Pathways in Streptomyces
The genus Streptomyces is known to harbor numerous biosynthetic gene clusters (BGCs) of potential utility in synthetic biology applications. However, it is often difficult to link uncharacterized BGCs with the secondary metabolites they produce. Proteomining refers to the strategy of identifying act...
Main Authors: | Darwin Linardi, Weiyi She, Qian Zhang, Yi Yu, Pei-Yuan Qian, Henry Lam |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-07-01
|
Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.913756/full |
Similar Items
-
Discovery, Bioactivity Evaluation, Biosynthetic Gene Cluster Identification, and Heterologous Expression of Novel Albofungin Derivatives
by: Weiyi She, et al.
Published: (2021-02-01) -
Screening and Isolation of a Novel Polyene-Producing Streptomyces Strain Inhibiting Phytopathogenic Fungi in the Soil Environment
by: Heung-Soon Park, et al.
Published: (2021-07-01) -
Elucidation of the di-c-glycosylation steps during biosynthesis of the antitumor antibiotic, kidamycin
by: Kyung Taek Heo, et al.
Published: (2022-08-01) -
Biosynthetic gene profiling and genomic potential of the novel photosynthetic marine bacterium Roseibaca domitiana
by: Giuliano Gattoni, et al.
Published: (2023-09-01) -
Diverse and Abundant Secondary Metabolism Biosynthetic Gene Clusters in the Genomes of Marine Sponge Derived Streptomyces spp. Isolates
by: Stephen A. Jackson, et al.
Published: (2018-02-01)