The Wound Healing Potential of Lignosus rhinocerus and Other Ethno-myco Wound Healing Agents
AbstractWound care has become increasingly important over the years. Various synthetic products for wound care treatment have been reported to cause toxic side effects and therefore natural products are in significant demand as they have minimal side effects. The presence of bioactive compounds in m...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-01-01
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| Series: | Mycobiology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/12298093.2022.2164641 |
| _version_ | 1797902744543035392 |
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| author | Hui-Yeng Y. Yap Mohammad Farhan Ariffeen Rosli Soon-Hao Tan Boon-Hong Kong Shin-Yee Fung |
| author_facet | Hui-Yeng Y. Yap Mohammad Farhan Ariffeen Rosli Soon-Hao Tan Boon-Hong Kong Shin-Yee Fung |
| author_sort | Hui-Yeng Y. Yap |
| collection | DOAJ |
| description | AbstractWound care has become increasingly important over the years. Various synthetic products for wound care treatment have been reported to cause toxic side effects and therefore natural products are in significant demand as they have minimal side effects. The presence of bioactive compounds in medicinal mushrooms contributes to various biological activities which assist in the early inflammatory phase, keratinocyte proliferation, and its migration enhancement which are pertinent to wound rehabilitation. Lignosus rhinocerus (tiger milk mushroom) can reduce the inflammation phase in wound healing by fighting off bacterial infection and modulating pro-inflammatory cytokines expression in the early stage to avoid prolonged inflammation and tissue damage. The antibacterial, immunomodulating, and anti-inflammatory activities exhibited by most macrofungi play a key role in enhancing wound healing. Several antibacterial and antifungal compounds sourced from traditional botanicals/products may prevent further complications and reoccurrence of injury to a wounded site. Scientific studies are actively underway to ascertain the potential use of macrofungi as a wound healing agent. |
| first_indexed | 2024-04-10T09:22:33Z |
| format | Article |
| id | doaj.art-d2de90ee5a664a7c9bd77f3b80a8f402 |
| institution | Directory Open Access Journal |
| issn | 1229-8093 2092-9323 |
| language | English |
| last_indexed | 2024-04-10T09:22:33Z |
| publishDate | 2023-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Mycobiology |
| spelling | doaj.art-d2de90ee5a664a7c9bd77f3b80a8f4022023-02-20T09:38:50ZengTaylor & Francis GroupMycobiology1229-80932092-93232023-01-0151111510.1080/12298093.2022.2164641The Wound Healing Potential of Lignosus rhinocerus and Other Ethno-myco Wound Healing AgentsHui-Yeng Y. Yap0Mohammad Farhan Ariffeen Rosli1Soon-Hao Tan2Boon-Hong Kong3Shin-Yee Fung4Department of Oral Biology and Biomedical Sciences, Faculty of Dentistry, MAHSA University, Bandar Saujana Putra, Selangor, MalaysiaDepartment of Oral Biology and Biomedical Sciences, Faculty of Dentistry, MAHSA University, Bandar Saujana Putra, Selangor, MalaysiaDepartment of Biomedical Science, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, MalaysiaCentre of Excellence for Research in AIDS (CERiA), Department of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, MalaysiaMedicinal Mushroom Research Group (MMRG), Department of Molecular Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, MalaysiaAbstractWound care has become increasingly important over the years. Various synthetic products for wound care treatment have been reported to cause toxic side effects and therefore natural products are in significant demand as they have minimal side effects. The presence of bioactive compounds in medicinal mushrooms contributes to various biological activities which assist in the early inflammatory phase, keratinocyte proliferation, and its migration enhancement which are pertinent to wound rehabilitation. Lignosus rhinocerus (tiger milk mushroom) can reduce the inflammation phase in wound healing by fighting off bacterial infection and modulating pro-inflammatory cytokines expression in the early stage to avoid prolonged inflammation and tissue damage. The antibacterial, immunomodulating, and anti-inflammatory activities exhibited by most macrofungi play a key role in enhancing wound healing. Several antibacterial and antifungal compounds sourced from traditional botanicals/products may prevent further complications and reoccurrence of injury to a wounded site. Scientific studies are actively underway to ascertain the potential use of macrofungi as a wound healing agent.https://www.tandfonline.com/doi/10.1080/12298093.2022.2164641Macrofungiethnobotanical useswound healingLignosus rhinocerusTiger milk mushroom |
| spellingShingle | Hui-Yeng Y. Yap Mohammad Farhan Ariffeen Rosli Soon-Hao Tan Boon-Hong Kong Shin-Yee Fung The Wound Healing Potential of Lignosus rhinocerus and Other Ethno-myco Wound Healing Agents Mycobiology Macrofungi ethnobotanical uses wound healing Lignosus rhinocerus Tiger milk mushroom |
| title | The Wound Healing Potential of Lignosus rhinocerus and Other Ethno-myco Wound Healing Agents |
| title_full | The Wound Healing Potential of Lignosus rhinocerus and Other Ethno-myco Wound Healing Agents |
| title_fullStr | The Wound Healing Potential of Lignosus rhinocerus and Other Ethno-myco Wound Healing Agents |
| title_full_unstemmed | The Wound Healing Potential of Lignosus rhinocerus and Other Ethno-myco Wound Healing Agents |
| title_short | The Wound Healing Potential of Lignosus rhinocerus and Other Ethno-myco Wound Healing Agents |
| title_sort | wound healing potential of lignosus rhinocerus and other ethno myco wound healing agents |
| topic | Macrofungi ethnobotanical uses wound healing Lignosus rhinocerus Tiger milk mushroom |
| url | https://www.tandfonline.com/doi/10.1080/12298093.2022.2164641 |
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