A Review on Microfluidic Platforms Applied to Nerve Regeneration
In recent decades, microfluidics have significantly advanced nerve regeneration research. Microfluidic devices can provide an accurate simulation of in vivo microenvironment for different research purposes such as analyzing myelin growth inhibitory factors, screening drugs, assessing nerve growth fa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Applied Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3417/12/7/3534 |
| _version_ | 1827624396474286080 |
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| author | Chuankai Dai Xiaoming Liu Rongyu Tang Jiping He Tatsuo Arai |
| author_facet | Chuankai Dai Xiaoming Liu Rongyu Tang Jiping He Tatsuo Arai |
| author_sort | Chuankai Dai |
| collection | DOAJ |
| description | In recent decades, microfluidics have significantly advanced nerve regeneration research. Microfluidic devices can provide an accurate simulation of in vivo microenvironment for different research purposes such as analyzing myelin growth inhibitory factors, screening drugs, assessing nerve growth factors, and exploring mechanisms of neural injury and regeneration. The microfluidic platform offers technical supports for nerve regeneration that enable precise spatio-temporal control of cells, such as neuron isolation, single-cell manipulation, neural patterning, and axon guidance. In this paper, we review the development and recent advances of microfluidic platforms for nerve regeneration research. |
| first_indexed | 2024-03-09T12:07:04Z |
| format | Article |
| id | doaj.art-d2dec8b5834e4b1095d607e96b18fd57 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T12:07:04Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-d2dec8b5834e4b1095d607e96b18fd572023-11-30T22:57:03ZengMDPI AGApplied Sciences2076-34172022-03-01127353410.3390/app12073534A Review on Microfluidic Platforms Applied to Nerve RegenerationChuankai Dai0Xiaoming Liu1Rongyu Tang2Jiping He3Tatsuo Arai4Key Laboratory of Biomimetic Robots and Systems, Ministry of Education, State Key Laboratory of Intelligent Control and Decision of Complex System, Beijing Advanced Innovation Center for Intelligent Robots and Systems, Beijing Institute of Technology, Beijing 100081, ChinaKey Laboratory of Biomimetic Robots and Systems, Ministry of Education, State Key Laboratory of Intelligent Control and Decision of Complex System, Beijing Advanced Innovation Center for Intelligent Robots and Systems, Beijing Institute of Technology, Beijing 100081, ChinaKey Laboratory of Biomimetic Robots and Systems, Ministry of Education, State Key Laboratory of Intelligent Control and Decision of Complex System, Beijing Advanced Innovation Center for Intelligent Robots and Systems, Beijing Institute of Technology, Beijing 100081, ChinaKey Laboratory of Biomimetic Robots and Systems, Ministry of Education, State Key Laboratory of Intelligent Control and Decision of Complex System, Beijing Advanced Innovation Center for Intelligent Robots and Systems, Beijing Institute of Technology, Beijing 100081, ChinaKey Laboratory of Biomimetic Robots and Systems, Ministry of Education, State Key Laboratory of Intelligent Control and Decision of Complex System, Beijing Advanced Innovation Center for Intelligent Robots and Systems, Beijing Institute of Technology, Beijing 100081, ChinaIn recent decades, microfluidics have significantly advanced nerve regeneration research. Microfluidic devices can provide an accurate simulation of in vivo microenvironment for different research purposes such as analyzing myelin growth inhibitory factors, screening drugs, assessing nerve growth factors, and exploring mechanisms of neural injury and regeneration. The microfluidic platform offers technical supports for nerve regeneration that enable precise spatio-temporal control of cells, such as neuron isolation, single-cell manipulation, neural patterning, and axon guidance. In this paper, we review the development and recent advances of microfluidic platforms for nerve regeneration research.https://www.mdpi.com/2076-3417/12/7/3534microfluidic devicenerve regenerationnerve repairaxon regrowthneurite outgrowthaxon guidance |
| spellingShingle | Chuankai Dai Xiaoming Liu Rongyu Tang Jiping He Tatsuo Arai A Review on Microfluidic Platforms Applied to Nerve Regeneration Applied Sciences microfluidic device nerve regeneration nerve repair axon regrowth neurite outgrowth axon guidance |
| title | A Review on Microfluidic Platforms Applied to Nerve Regeneration |
| title_full | A Review on Microfluidic Platforms Applied to Nerve Regeneration |
| title_fullStr | A Review on Microfluidic Platforms Applied to Nerve Regeneration |
| title_full_unstemmed | A Review on Microfluidic Platforms Applied to Nerve Regeneration |
| title_short | A Review on Microfluidic Platforms Applied to Nerve Regeneration |
| title_sort | review on microfluidic platforms applied to nerve regeneration |
| topic | microfluidic device nerve regeneration nerve repair axon regrowth neurite outgrowth axon guidance |
| url | https://www.mdpi.com/2076-3417/12/7/3534 |
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