Making the most of methylation
A high-throughput screening approach based on a protein microarray reveals that many human transcription factors interact specifically with methylated promoter sequences.
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Format: | Article |
Language: | English |
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eLife Sciences Publications Ltd
2013-09-01
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Series: | eLife |
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Online Access: | https://elifesciences.org/articles/01387 |
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author | Michiel Vermeulen |
author_facet | Michiel Vermeulen |
author_sort | Michiel Vermeulen |
collection | DOAJ |
description | A high-throughput screening approach based on a protein microarray reveals that many human transcription factors interact specifically with methylated promoter sequences. |
first_indexed | 2024-04-11T09:06:34Z |
format | Article |
id | doaj.art-d2e1e386628a41519f6e1d4d59ab8740 |
institution | Directory Open Access Journal |
issn | 2050-084X |
language | English |
last_indexed | 2024-04-11T09:06:34Z |
publishDate | 2013-09-01 |
publisher | eLife Sciences Publications Ltd |
record_format | Article |
series | eLife |
spelling | doaj.art-d2e1e386628a41519f6e1d4d59ab87402022-12-22T04:32:37ZengeLife Sciences Publications LtdeLife2050-084X2013-09-01210.7554/eLife.01387Making the most of methylationMichiel Vermeulen0Department of Molecular Cancer Research, University Medical Center Utrecht, Utrecht, NetherlandsA high-throughput screening approach based on a protein microarray reveals that many human transcription factors interact specifically with methylated promoter sequences.https://elifesciences.org/articles/01387DNA methylationprotein-DNA interactionprotein microarraytranscription factorepigenetictranscription regulation |
spellingShingle | Michiel Vermeulen Making the most of methylation eLife DNA methylation protein-DNA interaction protein microarray transcription factor epigenetic transcription regulation |
title | Making the most of methylation |
title_full | Making the most of methylation |
title_fullStr | Making the most of methylation |
title_full_unstemmed | Making the most of methylation |
title_short | Making the most of methylation |
title_sort | making the most of methylation |
topic | DNA methylation protein-DNA interaction protein microarray transcription factor epigenetic transcription regulation |
url | https://elifesciences.org/articles/01387 |
work_keys_str_mv | AT michielvermeulen makingthemostofmethylation |