Making the most of methylation

A high-throughput screening approach based on a protein microarray reveals that many human transcription factors interact specifically with methylated promoter sequences.

Bibliographic Details
Main Author: Michiel Vermeulen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/01387
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author Michiel Vermeulen
author_facet Michiel Vermeulen
author_sort Michiel Vermeulen
collection DOAJ
description A high-throughput screening approach based on a protein microarray reveals that many human transcription factors interact specifically with methylated promoter sequences.
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spelling doaj.art-d2e1e386628a41519f6e1d4d59ab87402022-12-22T04:32:37ZengeLife Sciences Publications LtdeLife2050-084X2013-09-01210.7554/eLife.01387Making the most of methylationMichiel Vermeulen0Department of Molecular Cancer Research, University Medical Center Utrecht, Utrecht, NetherlandsA high-throughput screening approach based on a protein microarray reveals that many human transcription factors interact specifically with methylated promoter sequences.https://elifesciences.org/articles/01387DNA methylationprotein-DNA interactionprotein microarraytranscription factorepigenetictranscription regulation
spellingShingle Michiel Vermeulen
Making the most of methylation
eLife
DNA methylation
protein-DNA interaction
protein microarray
transcription factor
epigenetic
transcription regulation
title Making the most of methylation
title_full Making the most of methylation
title_fullStr Making the most of methylation
title_full_unstemmed Making the most of methylation
title_short Making the most of methylation
title_sort making the most of methylation
topic DNA methylation
protein-DNA interaction
protein microarray
transcription factor
epigenetic
transcription regulation
url https://elifesciences.org/articles/01387
work_keys_str_mv AT michielvermeulen makingthemostofmethylation