Social cognition in patients with schizophrenia spectrum and bipolar disorders with and without psychotic features
Background: Social cognition may be critical to the impoverished social functioning seen in serious mental illness. However, although social-cognitive deficits are consistently demonstrated in schizophrenia spectrum disorders (SSD), studies in bipolar disorder (BD) have produced inconsistent results...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2015-03-01
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| Series: | Schizophrenia Research: Cognition |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2215001314000304 |
| _version_ | 1818361246689263616 |
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| author | George C. Nitzburg Katherine E. Burdick Anil K. Malhotra Pamela DeRosse |
| author_facet | George C. Nitzburg Katherine E. Burdick Anil K. Malhotra Pamela DeRosse |
| author_sort | George C. Nitzburg |
| collection | DOAJ |
| description | Background: Social cognition may be critical to the impoverished social functioning seen in serious mental illness. However, although social-cognitive deficits are consistently demonstrated in schizophrenia spectrum disorders (SSD), studies in bipolar disorder (BD) have produced inconsistent results. This inconsistency may relate to symptom profiles of patients studied, particularly the presence or absence of psychotic features. Thus, we examined social cognition in bipolar disorder with psychotic features (BD+) versus without psychotic features (BD−) relative to SSD and controls.
Methods: A sample of 537 SSD patients, 85 BD+ patients, 37 BD− patients, and 309 controls were administered the MATRICS Consensus Cognitive Battery, including a social cognition measure, the managing emotions branch of the Mayer–Salovey–Caruso Emotional Intelligence Test (MSCEIT). Analyses of covariance compared MSCEIT performance between diagnostic groups while controlling for race, psychotropic medication status, and neurocognition.
Results: SSD but not BD− or BD+ patients showed significant MSCEIT deficits relative to controls.
Conclusions: MSCEIT deficits were found in SSD but not BD− or BD+, suggesting that social cognition may represent an underlying difference between SSD and BD. However, variance in MSCEIT performance among BD patients may also suggest latent BD subgroups characterized by social-cognitive deficits. Findings can help inform future investigations into how social cognition and social brain development differ between SSD and BD. |
| first_indexed | 2024-12-13T21:13:38Z |
| format | Article |
| id | doaj.art-d2e2413fec194485977145341bfc5987 |
| institution | Directory Open Access Journal |
| issn | 2215-0013 |
| language | English |
| last_indexed | 2024-12-13T21:13:38Z |
| publishDate | 2015-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Schizophrenia Research: Cognition |
| spelling | doaj.art-d2e2413fec194485977145341bfc59872022-12-21T23:31:18ZengElsevierSchizophrenia Research: Cognition2215-00132015-03-01212710.1016/j.scog.2014.12.003Social cognition in patients with schizophrenia spectrum and bipolar disorders with and without psychotic featuresGeorge C. Nitzburg0Katherine E. Burdick1Anil K. Malhotra2Pamela DeRosse3Center for Psychiatric Neuroscience, The Feinstein Institute for Medical Research, Manhasset, NY 11030, USAHofstra North Shore – LIJ School of Medicine, Departments of Psychiatry and Molecular Medicine, Hempstead, NY, 11550, USACenter for Psychiatric Neuroscience, The Feinstein Institute for Medical Research, Manhasset, NY 11030, USACenter for Psychiatric Neuroscience, The Feinstein Institute for Medical Research, Manhasset, NY 11030, USABackground: Social cognition may be critical to the impoverished social functioning seen in serious mental illness. However, although social-cognitive deficits are consistently demonstrated in schizophrenia spectrum disorders (SSD), studies in bipolar disorder (BD) have produced inconsistent results. This inconsistency may relate to symptom profiles of patients studied, particularly the presence or absence of psychotic features. Thus, we examined social cognition in bipolar disorder with psychotic features (BD+) versus without psychotic features (BD−) relative to SSD and controls. Methods: A sample of 537 SSD patients, 85 BD+ patients, 37 BD− patients, and 309 controls were administered the MATRICS Consensus Cognitive Battery, including a social cognition measure, the managing emotions branch of the Mayer–Salovey–Caruso Emotional Intelligence Test (MSCEIT). Analyses of covariance compared MSCEIT performance between diagnostic groups while controlling for race, psychotropic medication status, and neurocognition. Results: SSD but not BD− or BD+ patients showed significant MSCEIT deficits relative to controls. Conclusions: MSCEIT deficits were found in SSD but not BD− or BD+, suggesting that social cognition may represent an underlying difference between SSD and BD. However, variance in MSCEIT performance among BD patients may also suggest latent BD subgroups characterized by social-cognitive deficits. Findings can help inform future investigations into how social cognition and social brain development differ between SSD and BD.http://www.sciencedirect.com/science/article/pii/S2215001314000304Social cognitionSchizophrenia spectrumBipolar disorderPsychotic featuresMATRICS |
| spellingShingle | George C. Nitzburg Katherine E. Burdick Anil K. Malhotra Pamela DeRosse Social cognition in patients with schizophrenia spectrum and bipolar disorders with and without psychotic features Schizophrenia Research: Cognition Social cognition Schizophrenia spectrum Bipolar disorder Psychotic features MATRICS |
| title | Social cognition in patients with schizophrenia spectrum and bipolar disorders with and without psychotic features |
| title_full | Social cognition in patients with schizophrenia spectrum and bipolar disorders with and without psychotic features |
| title_fullStr | Social cognition in patients with schizophrenia spectrum and bipolar disorders with and without psychotic features |
| title_full_unstemmed | Social cognition in patients with schizophrenia spectrum and bipolar disorders with and without psychotic features |
| title_short | Social cognition in patients with schizophrenia spectrum and bipolar disorders with and without psychotic features |
| title_sort | social cognition in patients with schizophrenia spectrum and bipolar disorders with and without psychotic features |
| topic | Social cognition Schizophrenia spectrum Bipolar disorder Psychotic features MATRICS |
| url | http://www.sciencedirect.com/science/article/pii/S2215001314000304 |
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